Simendan structure

Simendan

TL;DR: Simendan (CAS 131741-08-7) is a chemical compound with molecular formula C14H12N6O and molecular weight 280.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-[[4-(4-methyl-6-oxo-4,5-dihydro-1H-pyridazin-3-yl)phenyl]hydrazinylidene]propanedinitrile

Also Known As: Simendan, LEVOSIMENDAN, Simendan [INN], dextrosimendan, simendanum

CAS: 131741-08-7
Molecular Formula C14H12N6O
Molecular Weight 280.11 g/mol
LogP 2.3
Topological Polar Surface Area 113.0 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 6
Rotatable Bonds 3
Exact Mass 280.10727
Heavy Atoms 21
Complexity 549.0

Chemical Identifiers

CAS Number 131741-08-7
SMILES CC1CC(=O)NN=C1C2=CC=C(C=C2)NN=C(C#N)C#N
InChIKey WHXMKTBCFHIYNQ-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 5 IPC patent classification(s) across the SureChEMBL global patent database.

Agrochemicals (1 patents) Analytical Reagents (5 patents) Heterocyclic Building Blocks (43 patents) Organic Building Blocks (4 patents) Pharmaceutical Intermediates (268 patents)

Product Overview

Simendan (CAS 131741-08-7), with molecular formula C14H12N6O and molecular weight 280.11 g/mol. IUPAC: 2-[[4-(4-methyl-6-oxo-4,5-dihydro-1H-pyridazin-3-yl)phenyl]hydrazinylidene]propanedinitrile.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Simendan

XLogP
2.3
TPSA (Topological Polar Surface Area)
113.0
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
6
Rotatable Bonds
3
Heavy Atoms
21
Complexity
549.0
Exact Mass
280.10727
Monoisotopic Mass
280.10727
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Simendan

The XLogP value of 2.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Simendan. The TPSA of 113.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Simendan. Following Lipinski's Rule of Five, Simendan has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Simendan?

The CAS number of Simendan is 131741-08-7.

What is the molecular formula of Simendan?

The molecular formula of Simendan is C14H12N6O.

What is the molecular weight of Simendan?

The molecular weight of Simendan is 280.11 g/mol.

Where can I buy Simendan?

You can request a quote for Simendan directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Simendan?

Yes, KEHONG BIO provides custom synthesis services for Simendan and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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