N-(4-hydroxymethylphenyl)-3,3-difluoroazetidin-2-one
TL;DR: N-(4-hydroxymethylphenyl)-3,3-difluoroazetidin-2-one (CAS 131230-79-0) is a chemical compound with molecular formula C10H9F2NO2 and molecular weight 213.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3,3-difluoro-1-[4-(hydroxymethyl)phenyl]azetidin-2-one
Also Known As: N-(4-hydroxymethylphenyl)-3,3-difluoroazetidin-2-one, 3,3-difluoro-1-[4-(hydroxymethyl)phenyl]azetidin-2-one, 2-Azetidinone, 3,3-difluoro-1-[4-(hydroxymethyl)phenyl]-
| Molecular Formula | C10H9F2NO2 |
|---|---|
| Molecular Weight | 213.06 g/mol |
| LogP | 1.1608 |
| Topological Polar Surface Area | 40.54 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 213.06013 |
| Heavy Atoms | 15 |
| Complexity | 388.9138 |
Chemical Identifiers
| CAS Number | 131230-79-0 |
|---|---|
| SMILES | C1C(C(=O)N1C2=CC=C(C=C2)CO)(F)F |
Product Overview
N-(4-hydroxymethylphenyl)-3,3-difluoroazetidin-2-one (CAS 131230-79-0), with molecular formula C10H9F2NO2 and molecular weight 213.06 g/mol. IUPAC: 3,3-difluoro-1-[4-(hydroxymethyl)phenyl]azetidin-2-one.
Chemical Property Profile of N-(4-hydroxymethylphenyl)-3,3-difluoroazetidin-2-one
Property Insights of N-(4-hydroxymethylphenyl)-3,3-difluoroazetidin-2-one
The XLogP value of 1.1608 suggests moderate lipophilicity, balancing water solubility and membrane permeability for N-(4-hydroxymethylphenyl)-3,3-difluoroazetidin-2-one. With a topological polar surface area (TPSA) of 40.54 Ų, N-(4-hydroxymethylphenyl)-3,3-difluoroazetidin-2-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(4-hydroxymethylphenyl)-3,3-difluoroazetidin-2-one has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(4-hydroxymethylphenyl)-3,3-difluoroazetidin-2-one?
The CAS number of N-(4-hydroxymethylphenyl)-3,3-difluoroazetidin-2-one is 131230-79-0.
What is the molecular formula of N-(4-hydroxymethylphenyl)-3,3-difluoroazetidin-2-one?
The molecular formula of N-(4-hydroxymethylphenyl)-3,3-difluoroazetidin-2-one is C10H9F2NO2.
What is the molecular weight of N-(4-hydroxymethylphenyl)-3,3-difluoroazetidin-2-one?
The molecular weight of N-(4-hydroxymethylphenyl)-3,3-difluoroazetidin-2-one is 213.06 g/mol.
Where can I buy N-(4-hydroxymethylphenyl)-3,3-difluoroazetidin-2-one?
You can request a quote for N-(4-hydroxymethylphenyl)-3,3-difluoroazetidin-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(4-hydroxymethylphenyl)-3,3-difluoroazetidin-2-one?
Yes, KEHONG BIO provides custom synthesis services for N-(4-hydroxymethylphenyl)-3,3-difluoroazetidin-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.