Lamivudine, (A+-)-trans-
TL;DR: Lamivudine, (A+-)-trans- (CAS 131086-22-1) is a chemical compound with molecular formula C8H11N3O3S and molecular weight 229.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-amino-1-[(2S,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one
Also Known As: 2'-Epi-Lamivudine, lamivudine, Lamivudine, (+/-)-trans-, (+/-)-trans-Lamivudine, 5'-Epi-lamivudine
| Molecular Formula | C8H11N3O3S |
|---|---|
| Molecular Weight | 229.05 g/mol |
| LogP | -0.5941 |
| Topological Polar Surface Area | 90.37 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 229.05211 |
| Heavy Atoms | 15 |
| Complexity | 408.36353 |
Chemical Identifiers
| CAS Number | 131086-22-1 |
|---|---|
| SMILES | C1[C@H](O[C@@H](S1)CO)N2C=CC(=NC2=O)N |
Product Overview
Lamivudine, (A+-)-trans- (CAS 131086-22-1), with molecular formula C8H11N3O3S and molecular weight 229.05 g/mol. IUPAC: 4-amino-1-[(2S,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one.
Chemical Property Profile of Lamivudine, (A+-)-trans-
Property Insights of Lamivudine, (A+-)-trans-
The XLogP value of -0.5941 indicates that Lamivudine, (A+-)-trans- is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 90.37 Ų falls within the moderate polarity range, balancing permeability and solubility for Lamivudine, (A+-)-trans-. Following Lipinski's Rule of Five, Lamivudine, (A+-)-trans- has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Lamivudine, (A+-)-trans-?
The CAS number of Lamivudine, (A+-)-trans- is 131086-22-1.
What is the molecular formula of Lamivudine, (A+-)-trans-?
The molecular formula of Lamivudine, (A+-)-trans- is C8H11N3O3S.
What is the molecular weight of Lamivudine, (A+-)-trans-?
The molecular weight of Lamivudine, (A+-)-trans- is 229.05 g/mol.
Where can I buy Lamivudine, (A+-)-trans-?
You can request a quote for Lamivudine, (A+-)-trans- directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Lamivudine, (A+-)-trans-?
Yes, KEHONG BIO provides custom synthesis services for Lamivudine, (A+-)-trans- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.