1-beta-D-Arabinofuranosyl-5-fluorouracil
TL;DR: 1-beta-D-Arabinofuranosyl-5-fluorouracil (CAS 131-06-6) is a chemical compound with molecular formula C9H11FN2O6 and molecular weight 262.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoropyrimidine-2,4-dione
Also Known As: 1-b-D-Arabinosyl-5-fluorouracil, 5-Fluorouracil arabinoside, 5-Fluoroarabinouridine, ARA-FU, 1-Beta-D-Arabinosyl-5-fluorouracil
| Molecular Formula | C9H11FN2O6 |
|---|---|
| Molecular Weight | 262.06 g/mol |
| LogP | -1.7 |
| Topological Polar Surface Area | 119.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 2 |
| Exact Mass | 262.06012 |
| Heavy Atoms | 18 |
| Complexity | 414.0 |
Chemical Identifiers
| CAS Number | 131-06-6 |
|---|---|
| SMILES | C1=C(C(=O)NC(=O)N1[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)O)F |
| InChIKey | FHIDNBAQOFJWCA-MNCSTQPFSA-N |
Patent-Derived Application Labels
Derived from 4 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
1-beta-D-Arabinofuranosyl-5-fluorouracil (CAS 131-06-6), with molecular formula C9H11FN2O6 and molecular weight 262.06 g/mol. IUPAC: 1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoropyrimidine-2,4-dione.
Chemical Property Profile of 1-beta-D-Arabinofuranosyl-5-fluorouracil
Property Insights of 1-beta-D-Arabinofuranosyl-5-fluorouracil
The XLogP value of -1.7 indicates that 1-beta-D-Arabinofuranosyl-5-fluorouracil is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 119.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-beta-D-Arabinofuranosyl-5-fluorouracil. Following Lipinski's Rule of Five, 1-beta-D-Arabinofuranosyl-5-fluorouracil has 4 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-beta-D-Arabinofuranosyl-5-fluorouracil?
The CAS number of 1-beta-D-Arabinofuranosyl-5-fluorouracil is 131-06-6.
What is the molecular formula of 1-beta-D-Arabinofuranosyl-5-fluorouracil?
The molecular formula of 1-beta-D-Arabinofuranosyl-5-fluorouracil is C9H11FN2O6.
What is the molecular weight of 1-beta-D-Arabinofuranosyl-5-fluorouracil?
The molecular weight of 1-beta-D-Arabinofuranosyl-5-fluorouracil is 262.06 g/mol.
Where can I buy 1-beta-D-Arabinofuranosyl-5-fluorouracil?
You can request a quote for 1-beta-D-Arabinofuranosyl-5-fluorouracil directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-beta-D-Arabinofuranosyl-5-fluorouracil?
Yes, KEHONG BIO provides custom synthesis services for 1-beta-D-Arabinofuranosyl-5-fluorouracil and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.