2-amino-7-hydroxy-4-(thiophen-2-yl)-4H-chromene-3-carbonitrile
TL;DR: 2-amino-7-hydroxy-4-(thiophen-2-yl)-4H-chromene-3-carbonitrile (CAS 130944-05-7) is a chemical compound with molecular formula C14H10N2O2S and molecular weight 270.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-amino-7-hydroxy-4-thiophen-2-yl-4H-chromene-3-carbonitrile
Also Known As: BAS 00779709, J2.653.419D, 2-amino-7-hydroxy-4-(thiophen-2-yl)-4H-chromene-3-carbonitrile, 2-Amino-7-hydroxy-4-thiophen-2-yl-4H-chromene-3-carbonitrile, 2-Amino-3-cyano-4-(2-thienyl)-7-hydroxy-4H-1-benzopyran
| Molecular Formula | C14H10N2O2S |
|---|---|
| Molecular Weight | 270.05 g/mol |
| LogP | 2.7 |
| Topological Polar Surface Area | 108.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 1 |
| Exact Mass | 270.0463 |
| Heavy Atoms | 19 |
| Complexity | 442.0 |
Chemical Identifiers
| CAS Number | 130944-05-7 |
|---|---|
| SMILES | C1=CSC(=C1)C2C3=C(C=C(C=C3)O)OC(=C2C#N)N |
| InChIKey | VAIWHJBXUXCDIR-UHFFFAOYSA-N |
Product Overview
2-amino-7-hydroxy-4-(thiophen-2-yl)-4H-chromene-3-carbonitrile (CAS 130944-05-7), with molecular formula C14H10N2O2S and molecular weight 270.05 g/mol. IUPAC: 2-amino-7-hydroxy-4-thiophen-2-yl-4H-chromene-3-carbonitrile.
Chemical Property Profile of 2-amino-7-hydroxy-4-(thiophen-2-yl)-4H-chromene-3-carbonitrile
Property Insights of 2-amino-7-hydroxy-4-(thiophen-2-yl)-4H-chromene-3-carbonitrile
The XLogP value of 2.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-amino-7-hydroxy-4-(thiophen-2-yl)-4H-chromene-3-carbonitrile. The TPSA of 108.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-amino-7-hydroxy-4-(thiophen-2-yl)-4H-chromene-3-carbonitrile. Following Lipinski's Rule of Five, 2-amino-7-hydroxy-4-(thiophen-2-yl)-4H-chromene-3-carbonitrile has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-amino-7-hydroxy-4-(thiophen-2-yl)-4H-chromene-3-carbonitrile?
The CAS number of 2-amino-7-hydroxy-4-(thiophen-2-yl)-4H-chromene-3-carbonitrile is 130944-05-7.
What is the molecular formula of 2-amino-7-hydroxy-4-(thiophen-2-yl)-4H-chromene-3-carbonitrile?
The molecular formula of 2-amino-7-hydroxy-4-(thiophen-2-yl)-4H-chromene-3-carbonitrile is C14H10N2O2S.
What is the molecular weight of 2-amino-7-hydroxy-4-(thiophen-2-yl)-4H-chromene-3-carbonitrile?
The molecular weight of 2-amino-7-hydroxy-4-(thiophen-2-yl)-4H-chromene-3-carbonitrile is 270.05 g/mol.
Where can I buy 2-amino-7-hydroxy-4-(thiophen-2-yl)-4H-chromene-3-carbonitrile?
You can request a quote for 2-amino-7-hydroxy-4-(thiophen-2-yl)-4H-chromene-3-carbonitrile directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-amino-7-hydroxy-4-(thiophen-2-yl)-4H-chromene-3-carbonitrile?
Yes, KEHONG BIO provides custom synthesis services for 2-amino-7-hydroxy-4-(thiophen-2-yl)-4H-chromene-3-carbonitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.