Nemazoline
TL;DR: Nemazoline (CAS 130759-56-7) is a chemical compound with molecular formula C10H11Cl2N3 and molecular weight 243.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2,6-dichloro-4-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline
Also Known As: nemazolina, Nemazoline [INN], nemazolinum, Nemazoline HCl, Nemazoline Free Base
| Molecular Formula | C10H11Cl2N3 |
|---|---|
| Molecular Weight | 243.03 g/mol |
| LogP | 1.4 |
| Topological Polar Surface Area | 50.4 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 243.033 |
| Heavy Atoms | 15 |
| Complexity | 245.0 |
Chemical Identifiers
| CAS Number | 130759-56-7 |
|---|---|
| SMILES | C1CN=C(N1)CC2=CC(=C(C(=C2)Cl)N)Cl |
| InChIKey | FXNNRWAIGIEAST-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Nemazoline (CAS 130759-56-7), with molecular formula C10H11Cl2N3 and molecular weight 243.03 g/mol. IUPAC: 2,6-dichloro-4-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline.
Chemical Property Profile of Nemazoline
Property Insights of Nemazoline
The XLogP value of 1.4 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Nemazoline. With a topological polar surface area (TPSA) of 50.4 Ų, Nemazoline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Nemazoline has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Nemazoline?
The CAS number of Nemazoline is 130759-56-7.
What is the molecular formula of Nemazoline?
The molecular formula of Nemazoline is C10H11Cl2N3.
What is the molecular weight of Nemazoline?
The molecular weight of Nemazoline is 243.03 g/mol.
Where can I buy Nemazoline?
You can request a quote for Nemazoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Nemazoline?
Yes, KEHONG BIO provides custom synthesis services for Nemazoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.