3'-Azido-3'-deoxy-2',3'-seco-2'-hydroxythymidine
TL;DR: 3'-Azido-3'-deoxy-2',3'-seco-2'-hydroxythymidine (CAS 130515-67-2) is a chemical compound with molecular formula C10H15N5O5 and molecular weight 285.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(1R)-1-[(2S)-1-azido-3-hydroxypropan-2-yl]oxy-2-hydroxyethyl]-5-methylpyrimidine-2,4-dione
Also Known As: 3'-Az-Seco-ribo-ddT, 3'-Azido-3'-deoxy-2',3'-seco-2'-hydroxythymidine, 2,4(1H,3H)-Pyrimidinedione, 1-(1-(2-azido-1-(hydroxymethyl)ethoxy)-2-hydroxyethyl)-5-methyl-, (S-(R*,S*))-, 1-[(1R)-1-[(1S)-1-(azidomethyl)-2-hydroxy-ethoxy]-2-hydroxy-ethyl]-5-methyl-pyrimidine-2,4-dione, 1-[(1R)-1-[(2S)-1-azido-3-hydroxypropan-2-yl]oxy-2-hydroxyethyl]-5-methylpyrimidine-2,4-dione
| Molecular Formula | C10H15N5O5 |
|---|---|
| Molecular Weight | 285.11 g/mol |
| LogP | -0.97628 |
| Topological Polar Surface Area | 153.31 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 7 |
| Exact Mass | 285.10733 |
| Heavy Atoms | 20 |
| Complexity | 602.79126 |
Chemical Identifiers
| CAS Number | 130515-67-2 |
|---|---|
| SMILES | CC1=CN(C(=O)NC1=O)[C@@H](CO)O[C@@H](CN=[N+]=[N-])CO |
Product Overview
3'-Azido-3'-deoxy-2',3'-seco-2'-hydroxythymidine (CAS 130515-67-2), with molecular formula C10H15N5O5 and molecular weight 285.11 g/mol. IUPAC: 1-[(1R)-1-[(2S)-1-azido-3-hydroxypropan-2-yl]oxy-2-hydroxyethyl]-5-methylpyrimidine-2,4-dione.
Chemical Property Profile of 3'-Azido-3'-deoxy-2',3'-seco-2'-hydroxythymidine
Property Insights of 3'-Azido-3'-deoxy-2',3'-seco-2'-hydroxythymidine
The XLogP value of -0.97628 indicates that 3'-Azido-3'-deoxy-2',3'-seco-2'-hydroxythymidine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 153.31 Ų indicates high polarity, suggesting 3'-Azido-3'-deoxy-2',3'-seco-2'-hydroxythymidine may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 3'-Azido-3'-deoxy-2',3'-seco-2'-hydroxythymidine has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3'-Azido-3'-deoxy-2',3'-seco-2'-hydroxythymidine?
The CAS number of 3'-Azido-3'-deoxy-2',3'-seco-2'-hydroxythymidine is 130515-67-2.
What is the molecular formula of 3'-Azido-3'-deoxy-2',3'-seco-2'-hydroxythymidine?
The molecular formula of 3'-Azido-3'-deoxy-2',3'-seco-2'-hydroxythymidine is C10H15N5O5.
What is the molecular weight of 3'-Azido-3'-deoxy-2',3'-seco-2'-hydroxythymidine?
The molecular weight of 3'-Azido-3'-deoxy-2',3'-seco-2'-hydroxythymidine is 285.11 g/mol.
Where can I buy 3'-Azido-3'-deoxy-2',3'-seco-2'-hydroxythymidine?
You can request a quote for 3'-Azido-3'-deoxy-2',3'-seco-2'-hydroxythymidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3'-Azido-3'-deoxy-2',3'-seco-2'-hydroxythymidine?
Yes, KEHONG BIO provides custom synthesis services for 3'-Azido-3'-deoxy-2',3'-seco-2'-hydroxythymidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.