3'-Hydroxymethyl Ara-T
TL;DR: 3'-Hydroxymethyl Ara-T (CAS 130351-55-2) is a chemical compound with molecular formula C11H16N2O6 and molecular weight 272.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(2R,3S,4S,5S)-3-hydroxy-4,5-bis(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
Also Known As: 3'-Hydroxymethyl Ara-T, 2,4(1H,3H)-Pyrimidinedione, 1-(3-deoxy-3-(hydroxymethyl)-beta-D-arabinofuranosyl)-5-methyl-, 3'-Deoxy-3'-C-(hydroxymethyl)-beta-D-arabino-pentofuranosyl thymine, 1-(3-Deoxy-3-hydroxymethyl-beta-D-arabinofuranosyl)thymine, 3'-Deoxy-3'-C-(hydroxymethyl)-.beta.-D-arabino-pentofuranosyl thymine
| Molecular Formula | C11H16N2O6 |
|---|---|
| Molecular Weight | 272.10 g/mol |
| LogP | -1.7 |
| Topological Polar Surface Area | 119.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 272.10083 |
| Heavy Atoms | 19 |
| Complexity | 423.0 |
Chemical Identifiers
| CAS Number | 130351-55-2 |
|---|---|
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2[C@H]([C@@H]([C@H](O2)CO)CO)O |
| InChIKey | SAQLIIXINWYWJX-BDNRQGISSA-N |
Product Overview
3'-Hydroxymethyl Ara-T (CAS 130351-55-2), with molecular formula C11H16N2O6 and molecular weight 272.10 g/mol. IUPAC: 1-[(2R,3S,4S,5S)-3-hydroxy-4,5-bis(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione.
Chemical Property Profile of 3'-Hydroxymethyl Ara-T
Property Insights of 3'-Hydroxymethyl Ara-T
The XLogP value of -1.7 indicates that 3'-Hydroxymethyl Ara-T is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 119.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 3'-Hydroxymethyl Ara-T. Following Lipinski's Rule of Five, 3'-Hydroxymethyl Ara-T has 4 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3'-Hydroxymethyl Ara-T?
The CAS number of 3'-Hydroxymethyl Ara-T is 130351-55-2.
What is the molecular formula of 3'-Hydroxymethyl Ara-T?
The molecular formula of 3'-Hydroxymethyl Ara-T is C11H16N2O6.
What is the molecular weight of 3'-Hydroxymethyl Ara-T?
The molecular weight of 3'-Hydroxymethyl Ara-T is 272.10 g/mol.
Where can I buy 3'-Hydroxymethyl Ara-T?
You can request a quote for 3'-Hydroxymethyl Ara-T directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3'-Hydroxymethyl Ara-T?
Yes, KEHONG BIO provides custom synthesis services for 3'-Hydroxymethyl Ara-T and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.