Amphotericin B 2-morpholinoethyl amide diaspartate structure

Amphotericin B 2-morpholinoethyl amide diaspartate

TL;DR: Amphotericin B 2-morpholinoethyl amide diaspartate (CAS 130176-10-2) is a chemical compound with molecular formula C61H99N5O25 and molecular weight 1301.66 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

bis((2S)-2-aminobutanedioic acid);(19E,21E,23E,25E,27E,29E,31E)-33-(4-amino-3,5-dihydroxy-6-methyloxan-2-yl)oxy-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-N-(2-morpholin-4-ylethyl)-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxamide

Also Known As: AB-2-Meada, Amphotericin B 2-morpholinoethyl amide diaspartate, (2S)-2-aminobutanedioic acid;(19E,21E,23E,25E,27E,29E,31E)-33-(4-amino-3,5-dihydroxy-6-methyloxan-2-yl)oxy-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-N-(2-morpholin-4-ylethyl)-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxamide, Amphotericin B, 16-decarboxy-16-(((2-(4-morpholinyl)ethyl)amino)carbonyl)-, L-aspartate (1:2) (salt), L-Aspartic acid, compd. with 16-decarboxy-16-(((2-(4-morpholinyl)ethyl)amino)carbonyl)amphotericin B (2:1)

CAS: 130176-10-2
Molecular Formula C61H99N5O25
Molecular Weight 1301.66 g/mol
LogP -2.1785
Topological Polar Surface Area 525.12 Ų
Hydrogen Bond Donors 18
Hydrogen Bond Acceptors 25
Rotatable Bonds 12
Exact Mass 1301.663
Heavy Atoms 91
Complexity 2390.8396

Chemical Identifiers

CAS Number 130176-10-2
SMILES CC1/C=C/C=C/C=C/C=C/C=C/C=C/C=C/C(CC2C(C(CC(O2)(CC(CC(C(CCC(CC(CC(=O)OC(C(C1O)C)C)O)O)O)O)O)O)O)C(=O)NCCN3CCOCC3)OC4C(C(C(C(O4)C)O)N)O.C([C@@H](C(=O)O)N)C(=O)O.C([C@@H](C(=O)O)N)C(=O)O

Product Overview

Amphotericin B 2-morpholinoethyl amide diaspartate (CAS 130176-10-2), with molecular formula C61H99N5O25 and molecular weight 1301.66 g/mol. IUPAC: bis((2S)-2-aminobutanedioic acid);(19E,21E,23E,25E,27E,29E,31E)-33-(4-amino-3,5-dihydroxy-6-methyloxan-2-yl)oxy-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-N-(2-morpholin-4-ylethyl)-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of Amphotericin B 2-morpholinoethyl amide diaspartate

XLogP
-2.1785
TPSA (Topological Polar Surface Area)
525.12
Hydrogen Bond Donors
18
Hydrogen Bond Acceptors
25
Rotatable Bonds
12
Heavy Atoms
91
Complexity
2390.8396
Exact Mass
1301.663
Monoisotopic Mass
1301.663
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Amphotericin B 2-morpholinoethyl amide diaspartate

The XLogP value of -2.1785 indicates that Amphotericin B 2-morpholinoethyl amide diaspartate is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 525.12 Ų indicates high polarity, suggesting Amphotericin B 2-morpholinoethyl amide diaspartate may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Amphotericin B 2-morpholinoethyl amide diaspartate has 18 hydrogen bond donor(s) and 25 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Amphotericin B 2-morpholinoethyl amide diaspartate?

The CAS number of Amphotericin B 2-morpholinoethyl amide diaspartate is 130176-10-2.

What is the molecular formula of Amphotericin B 2-morpholinoethyl amide diaspartate?

The molecular formula of Amphotericin B 2-morpholinoethyl amide diaspartate is C61H99N5O25.

What is the molecular weight of Amphotericin B 2-morpholinoethyl amide diaspartate?

The molecular weight of Amphotericin B 2-morpholinoethyl amide diaspartate is 1301.66 g/mol.

Where can I buy Amphotericin B 2-morpholinoethyl amide diaspartate?

You can request a quote for Amphotericin B 2-morpholinoethyl amide diaspartate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Amphotericin B 2-morpholinoethyl amide diaspartate?

Yes, KEHONG BIO provides custom synthesis services for Amphotericin B 2-morpholinoethyl amide diaspartate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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