4'-Azidothymidine
TL;DR: 4'-Azidothymidine (CAS 130108-72-4) is a chemical compound with molecular formula C10H13N5O5 and molecular weight 283.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(2R,4S,5R)-5-azido-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
Also Known As: 4'-Azidothymidine, ADRT, Thiopyronin cation, Thiopyronine cation, Thymidine, 4'-azido-
| Molecular Formula | C10H13N5O5 |
|---|---|
| Molecular Weight | 283.09 g/mol |
| LogP | -0.2 |
| Topological Polar Surface Area | 113.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 3 |
| Exact Mass | 283.09167 |
| Heavy Atoms | 20 |
| Complexity | 528.0 |
Chemical Identifiers
| CAS Number | 130108-72-4 |
|---|---|
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@](O2)(CO)N=[N+]=[N-])O |
| InChIKey | ZNPKSOLUIAAPQI-NYNCVSEMSA-N |
Product Overview
4'-Azidothymidine (CAS 130108-72-4), with molecular formula C10H13N5O5 and molecular weight 283.09 g/mol. IUPAC: 1-[(2R,4S,5R)-5-azido-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione.
Chemical Property Profile of 4'-Azidothymidine
Property Insights of 4'-Azidothymidine
The XLogP value of -0.2 indicates that 4'-Azidothymidine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 113.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 4'-Azidothymidine. Following Lipinski's Rule of Five, 4'-Azidothymidine has 3 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4'-Azidothymidine?
The CAS number of 4'-Azidothymidine is 130108-72-4.
What is the molecular formula of 4'-Azidothymidine?
The molecular formula of 4'-Azidothymidine is C10H13N5O5.
What is the molecular weight of 4'-Azidothymidine?
The molecular weight of 4'-Azidothymidine is 283.09 g/mol.
Where can I buy 4'-Azidothymidine?
You can request a quote for 4'-Azidothymidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4'-Azidothymidine?
Yes, KEHONG BIO provides custom synthesis services for 4'-Azidothymidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.