RM 49
TL;DR: RM 49 (CAS 129879-41-0) is a chemical compound with molecular formula C16H20N4O6 and molecular weight 364.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[(4S,6S,7S,8R)-10-hydroxy-7,13-dimethoxy-12-methyl-11-nitroso-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(13),9,11-trien-8-yl]methyl carbamate
Also Known As: RM 49, KST-1A1010, 8-((Aminocarbonyl)oxy)methyl-4,8a-dimethoxy-1,1a,2,8,8a,8b-hexahydro-7-hydroxy-5-methyl-6-nitrosoazirino(2',3'-3,4)-pyrrolo-(1,2-a)indole, [(4S,6S,7S,8R)-10-Hydroxy-7,13-dimethoxy-12-methyl-11-nitroso-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(13),9,11-trien-8-yl]methyl carbamate, [(1as,8r,8as,8bs)-7-hydroxy-4,8a-dimethoxy-5-methyl-6-nitroso-1,1a,2,8,8a,8b-hexahydroazireno[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methyl carbamate
| Molecular Formula | C16H20N4O6 |
|---|---|
| Molecular Weight | 364.14 g/mol |
| LogP | 0.2 |
| Topological Polar Surface Area | 146.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 5 |
| Exact Mass | 364.13828 |
| Heavy Atoms | 26 |
| Complexity | 607.0 |
Chemical Identifiers
| CAS Number | 129879-41-0 |
|---|---|
| SMILES | CC1=C(C(=C2[C@@H]([C@@]3([C@@H]4[C@@H](N4)CN3C2=C1OC)OC)COC(=O)N)O)N=O |
| InChIKey | NVDDGNSLJMPYKZ-HHBNPUPASA-N |
Product Overview
RM 49 (CAS 129879-41-0), with molecular formula C16H20N4O6 and molecular weight 364.14 g/mol. IUPAC: [(4S,6S,7S,8R)-10-hydroxy-7,13-dimethoxy-12-methyl-11-nitroso-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(13),9,11-trien-8-yl]methyl carbamate.
Chemical Property Profile of RM 49
Property Insights of RM 49
The XLogP value of 0.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for RM 49. The TPSA of 146.0 Ų indicates high polarity, suggesting RM 49 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, RM 49 has 3 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of RM 49?
The CAS number of RM 49 is 129879-41-0.
What is the molecular formula of RM 49?
The molecular formula of RM 49 is C16H20N4O6.
What is the molecular weight of RM 49?
The molecular weight of RM 49 is 364.14 g/mol.
Where can I buy RM 49?
You can request a quote for RM 49 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for RM 49?
Yes, KEHONG BIO provides custom synthesis services for RM 49 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.