Histidyl-aspartyl-glutamyl-leucine structure

Histidyl-aspartyl-glutamyl-leucine

TL;DR: Histidyl-aspartyl-glutamyl-leucine (CAS 129623-52-5) is a chemical compound with molecular formula C21H32N6O9 and molecular weight 512.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]-3-carboxypropanoyl]amino]-4-carboxybutanoyl]amino]-4-methylpentanoic acid

Also Known As: Hdel sequence, His-asp-glu-leu, Histidyl-aspartyl-glutamyl-leucine, (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]-3-carboxypropanoyl]amino]-4-carboxybutanoyl]amino]-4-methylpentanoic acid, L-Histidyl-L-alpha-aspartyl-L-alpha-glutamyl-L-leucine

CAS: 129623-52-5
Molecular Formula C21H32N6O9
Molecular Weight 512.22 g/mol
LogP -4.1
Topological Polar Surface Area 254.0 Ų
Hydrogen Bond Donors 8
Hydrogen Bond Acceptors 11
Rotatable Bonds 16
Exact Mass 512.2231
Heavy Atoms 36
Complexity 822.0

Chemical Identifiers

CAS Number 129623-52-5
SMILES CC(C)C[C@@H](C(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC1=CN=CN1)N
InChIKey INOZZBHURUDQQR-AJNGGQMLSA-N

Product Overview

Histidyl-aspartyl-glutamyl-leucine (CAS 129623-52-5), with molecular formula C21H32N6O9 and molecular weight 512.22 g/mol. IUPAC: (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]-3-carboxypropanoyl]amino]-4-carboxybutanoyl]amino]-4-methylpentanoic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Histidyl-aspartyl-glutamyl-leucine

XLogP
-4.1
TPSA (Topological Polar Surface Area)
254.0
Hydrogen Bond Donors
8
Hydrogen Bond Acceptors
11
Rotatable Bonds
16
Heavy Atoms
36
Complexity
822.0
Exact Mass
512.2231
Monoisotopic Mass
512.2231
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Histidyl-aspartyl-glutamyl-leucine

The XLogP value of -4.1 indicates that Histidyl-aspartyl-glutamyl-leucine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 254.0 Ų indicates high polarity, suggesting Histidyl-aspartyl-glutamyl-leucine may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Histidyl-aspartyl-glutamyl-leucine has 8 hydrogen bond donor(s) and 11 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Histidyl-aspartyl-glutamyl-leucine?

The CAS number of Histidyl-aspartyl-glutamyl-leucine is 129623-52-5.

What is the molecular formula of Histidyl-aspartyl-glutamyl-leucine?

The molecular formula of Histidyl-aspartyl-glutamyl-leucine is C21H32N6O9.

What is the molecular weight of Histidyl-aspartyl-glutamyl-leucine?

The molecular weight of Histidyl-aspartyl-glutamyl-leucine is 512.22 g/mol.

Where can I buy Histidyl-aspartyl-glutamyl-leucine?

You can request a quote for Histidyl-aspartyl-glutamyl-leucine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Histidyl-aspartyl-glutamyl-leucine?

Yes, KEHONG BIO provides custom synthesis services for Histidyl-aspartyl-glutamyl-leucine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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