FK 1052
TL;DR: FK 1052 (CAS 129299-89-4) is a chemical compound with molecular formula C18H19N3O and molecular weight 293.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
10-methyl-7-[(5-methyl-1H-imidazol-4-yl)methyl]-8,9-dihydro-7H-pyrido[1,2-a]indol-6-one
Also Known As: Fabesetron, Fabesetron [INN], FK 1052, PDSP1_000568, PDSP2_000566
| Molecular Formula | C18H19N3O |
|---|---|
| Molecular Weight | 293.15 g/mol |
| LogP | 3.2 |
| Topological Polar Surface Area | 50.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 293.1528 |
| Heavy Atoms | 22 |
| Complexity | 440.0 |
Chemical Identifiers
| CAS Number | 129299-89-4 |
|---|---|
| SMILES | CC1=C2CCC(C(=O)N2C3=CC=CC=C13)CC4=C(NC=N4)C |
| InChIKey | AEKQMJRJRAHOAP-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
FK 1052 (CAS 129299-89-4), with molecular formula C18H19N3O and molecular weight 293.15 g/mol. IUPAC: 10-methyl-7-[(5-methyl-1H-imidazol-4-yl)methyl]-8,9-dihydro-7H-pyrido[1,2-a]indol-6-one.
Chemical Property Profile of FK 1052
Property Insights of FK 1052
The XLogP value of 3.2 indicates that FK 1052 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 50.7 Ų, FK 1052 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, FK 1052 has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of FK 1052?
The CAS number of FK 1052 is 129299-89-4.
What is the molecular formula of FK 1052?
The molecular formula of FK 1052 is C18H19N3O.
What is the molecular weight of FK 1052?
The molecular weight of FK 1052 is 293.15 g/mol.
Where can I buy FK 1052?
You can request a quote for FK 1052 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for FK 1052?
Yes, KEHONG BIO provides custom synthesis services for FK 1052 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.