Loteprednol
TL;DR: Loteprednol (CAS 129260-79-3) is a chemical compound with molecular formula C21H27ClO5 and molecular weight 394.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
chloromethyl (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-17-carboxylate
Also Known As: loteprednol, Loteprednolum, Loteprednol (INN), Loteprednol [INN:BAN], Loteprednol etabonate
| Molecular Formula | C21H27ClO5 |
|---|---|
| Molecular Weight | 394.15 g/mol |
| LogP | 2.7357 |
| Topological Polar Surface Area | 83.83 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 394.1547 |
| Heavy Atoms | 27 |
| Complexity | 744.854 |
Chemical Identifiers
| CAS Number | 129260-79-3 |
|---|---|
| SMILES | C[C@]12C[C@@H]([C@H]3[C@H]([C@@H]1CC[C@@]2(C(=O)OCCl)O)CCC4=CC(=O)C=C[C@]34C)O |
Product Overview
Loteprednol (CAS 129260-79-3), with molecular formula C21H27ClO5 and molecular weight 394.15 g/mol. IUPAC: chloromethyl (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-17-carboxylate.
Chemical Property Profile of Loteprednol
Property Insights of Loteprednol
The XLogP value of 2.7357 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Loteprednol. The TPSA of 83.83 Ų falls within the moderate polarity range, balancing permeability and solubility for Loteprednol. Following Lipinski's Rule of Five, Loteprednol has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Loteprednol?
The CAS number of Loteprednol is 129260-79-3.
What is the molecular formula of Loteprednol?
The molecular formula of Loteprednol is C21H27ClO5.
What is the molecular weight of Loteprednol?
The molecular weight of Loteprednol is 394.15 g/mol.
Where can I buy Loteprednol?
You can request a quote for Loteprednol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Loteprednol?
Yes, KEHONG BIO provides custom synthesis services for Loteprednol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.