DiNa-5'-O-Phosphonomethyl-ddU
TL;DR: DiNa-5'-O-Phosphonomethyl-ddU (CAS 129151-66-2) is a chemical compound with molecular formula C10H13N2O7P-2 and molecular weight 304.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(2R,5S)-5-(phosphonatomethoxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
Also Known As: DiNa-5'-O-Phosphonomethyl-ddU, Disodium 5'-O-(Phosphonomethyl)-2',3'-dideoxyuridine, [(2S,5R)-5-(2,4-dioxopyrimidin-1-yl)tetrahydrofuran-2-yl]methoxymethylphosphonic acid, Uridine, 2',3'-dideoxy-5'-O-(phosphonomethyl)-, disodium salt, 1-[(2R,5S)-5-(phosphonatomethoxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
| Molecular Formula | C10H13N2O7P-2 |
|---|---|
| Molecular Weight | 304.05 g/mol |
| LogP | -2.2 |
| Topological Polar Surface Area | 131.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 4 |
| Exact Mass | 304.04605 |
| Heavy Atoms | 20 |
| Complexity | 463.0 |
Chemical Identifiers
| CAS Number | 129151-66-2 |
|---|---|
| SMILES | C1C[C@@H](O[C@@H]1COCP(=O)([O-])[O-])N2C=CC(=O)NC2=O |
| InChIKey | GLMGVORAWLDEJT-IONNQARKSA-L |
Product Overview
DiNa-5'-O-Phosphonomethyl-ddU (CAS 129151-66-2), with molecular formula C10H13N2O7P-2 and molecular weight 304.05 g/mol. IUPAC: 1-[(2R,5S)-5-(phosphonatomethoxymethyl)oxolan-2-yl]pyrimidine-2,4-dione.
Chemical Property Profile of DiNa-5'-O-Phosphonomethyl-ddU
Property Insights of DiNa-5'-O-Phosphonomethyl-ddU
The XLogP value of -2.2 indicates that DiNa-5'-O-Phosphonomethyl-ddU is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 131.0 Ų falls within the moderate polarity range, balancing permeability and solubility for DiNa-5'-O-Phosphonomethyl-ddU. Following Lipinski's Rule of Five, DiNa-5'-O-Phosphonomethyl-ddU has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of DiNa-5'-O-Phosphonomethyl-ddU?
The CAS number of DiNa-5'-O-Phosphonomethyl-ddU is 129151-66-2.
What is the molecular formula of DiNa-5'-O-Phosphonomethyl-ddU?
The molecular formula of DiNa-5'-O-Phosphonomethyl-ddU is C10H13N2O7P-2.
What is the molecular weight of DiNa-5'-O-Phosphonomethyl-ddU?
The molecular weight of DiNa-5'-O-Phosphonomethyl-ddU is 304.05 g/mol.
Where can I buy DiNa-5'-O-Phosphonomethyl-ddU?
You can request a quote for DiNa-5'-O-Phosphonomethyl-ddU directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for DiNa-5'-O-Phosphonomethyl-ddU?
Yes, KEHONG BIO provides custom synthesis services for DiNa-5'-O-Phosphonomethyl-ddU and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.