Thymidine, 3'-azido-3'-deoxy-5'-O-(phosphonomethyl)-
TL;DR: Thymidine, 3'-azido-3'-deoxy-5'-O-(phosphonomethyl)- (CAS 129151-65-1) is a chemical compound with molecular formula C11H16N5O7P and molecular weight 361.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxymethylphosphonic acid
Also Known As: 5'-Phosphonomethylene-3'-AzdT, 5'-Phosphonomethylene-3'-azido-deoxythymidine, Thymidine, 3'-azido-3'-deoxy-5'-O-(phosphonomethyl)-, 3'-Azido-3'-deoxy-5'-O-(phosphonomethyl)thymidine, [(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)tetrahydrofuran-2-yl]methoxymethylphosphonic acid
| Molecular Formula | C11H16N5O7P |
|---|---|
| Molecular Weight | 361.08 g/mol |
| LogP | -1.1 |
| Topological Polar Surface Area | 140.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 6 |
| Exact Mass | 361.07874 |
| Heavy Atoms | 24 |
| Complexity | 655.0 |
Chemical Identifiers
| CAS Number | 129151-65-1 |
|---|---|
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)COCP(=O)(O)O)N=[N+]=[N-] |
| InChIKey | NOEYTKCEXDEMEO-DJLDLDEBSA-N |
Product Overview
Thymidine, 3'-azido-3'-deoxy-5'-O-(phosphonomethyl)- (CAS 129151-65-1), with molecular formula C11H16N5O7P and molecular weight 361.08 g/mol. IUPAC: [(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxymethylphosphonic acid.
Chemical Property Profile of Thymidine, 3'-azido-3'-deoxy-5'-O-(phosphonomethyl)-
Property Insights of Thymidine, 3'-azido-3'-deoxy-5'-O-(phosphonomethyl)-
The XLogP value of -1.1 indicates that Thymidine, 3'-azido-3'-deoxy-5'-O-(phosphonomethyl)- is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 140.0 Ų indicates high polarity, suggesting Thymidine, 3'-azido-3'-deoxy-5'-O-(phosphonomethyl)- may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Thymidine, 3'-azido-3'-deoxy-5'-O-(phosphonomethyl)- has 3 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Thymidine, 3'-azido-3'-deoxy-5'-O-(phosphonomethyl)-?
The CAS number of Thymidine, 3'-azido-3'-deoxy-5'-O-(phosphonomethyl)- is 129151-65-1.
What is the molecular formula of Thymidine, 3'-azido-3'-deoxy-5'-O-(phosphonomethyl)-?
The molecular formula of Thymidine, 3'-azido-3'-deoxy-5'-O-(phosphonomethyl)- is C11H16N5O7P.
What is the molecular weight of Thymidine, 3'-azido-3'-deoxy-5'-O-(phosphonomethyl)-?
The molecular weight of Thymidine, 3'-azido-3'-deoxy-5'-O-(phosphonomethyl)- is 361.08 g/mol.
Where can I buy Thymidine, 3'-azido-3'-deoxy-5'-O-(phosphonomethyl)-?
You can request a quote for Thymidine, 3'-azido-3'-deoxy-5'-O-(phosphonomethyl)- directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Thymidine, 3'-azido-3'-deoxy-5'-O-(phosphonomethyl)-?
Yes, KEHONG BIO provides custom synthesis services for Thymidine, 3'-azido-3'-deoxy-5'-O-(phosphonomethyl)- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.