11-Methoxy-16-fluoroestradiol
TL;DR: 11-Methoxy-16-fluoroestradiol (CAS 129000-37-9) is a chemical compound with molecular formula C19H25FO3 and molecular weight 320.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(8S,9S,11S,13S,14S,16R,17R)-16-fluoro-11-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
Also Known As: 11-Meo-fes, 11-Methoxy-16-fluoroestradiol, KST-1A1043, 11beta-methoxy-16alpha-fluoro-Estradiol, 11beta-Methoxy-16alpha-fluoro-17beta-estradiol
| Molecular Formula | C19H25FO3 |
|---|---|
| Molecular Weight | 320.18 g/mol |
| LogP | 2.9 |
| Topological Polar Surface Area | 49.7 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 320.17877 |
| Heavy Atoms | 23 |
| Complexity | 458.0 |
Chemical Identifiers
| CAS Number | 129000-37-9 |
|---|---|
| SMILES | C[C@]12C[C@@H]([C@H]3[C@H]([C@@H]1C[C@H]([C@@H]2O)F)CCC4=C3C=CC(=C4)O)OC |
| InChIKey | HPWNWIGEGOPWMQ-RUOITVIXSA-N |
Product Overview
11-Methoxy-16-fluoroestradiol (CAS 129000-37-9), with molecular formula C19H25FO3 and molecular weight 320.18 g/mol. IUPAC: (8S,9S,11S,13S,14S,16R,17R)-16-fluoro-11-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol.
Chemical Property Profile of 11-Methoxy-16-fluoroestradiol
Property Insights of 11-Methoxy-16-fluoroestradiol
The XLogP value of 2.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 11-Methoxy-16-fluoroestradiol. With a topological polar surface area (TPSA) of 49.7 Ų, 11-Methoxy-16-fluoroestradiol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 11-Methoxy-16-fluoroestradiol has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 11-Methoxy-16-fluoroestradiol?
The CAS number of 11-Methoxy-16-fluoroestradiol is 129000-37-9.
What is the molecular formula of 11-Methoxy-16-fluoroestradiol?
The molecular formula of 11-Methoxy-16-fluoroestradiol is C19H25FO3.
What is the molecular weight of 11-Methoxy-16-fluoroestradiol?
The molecular weight of 11-Methoxy-16-fluoroestradiol is 320.18 g/mol.
Where can I buy 11-Methoxy-16-fluoroestradiol?
You can request a quote for 11-Methoxy-16-fluoroestradiol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 11-Methoxy-16-fluoroestradiol?
Yes, KEHONG BIO provides custom synthesis services for 11-Methoxy-16-fluoroestradiol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.