(Z)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-3-cyclopropyl-1H-pyrazole-5-carbohydrazide
TL;DR: (Z)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-3-cyclopropyl-1H-pyrazole-5-carbohydrazide (CAS 1285635-46-2) is a chemical compound with molecular formula C13H13ClN4OS and molecular weight 308.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(Z)-1-(5-chlorothiophen-2-yl)ethylideneamino]-5-cyclopropyl-1H-pyrazole-3-carboxamide
Also Known As: (Z)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-3-cyclopropyl-1H-pyrazole-5-carbohydrazide, F1092-1110, N-[(Z)-1-(5-chlorothiophen-2-yl)ethylideneamino]-5-cyclopropyl-1H-pyrazole-3-carboxamide, N'-[(1Z)-1-(5-chlorothiophen-2-yl)ethylidene]-3-cyclopropyl-1H-pyrazole-5-carbohydrazide, N-[(1Z)-2-(5-chloro(2-thienyl))-1-azaprop-1-enyl](3-cyclopropylpyrazol-5-yl)ca rboxamide
| Molecular Formula | C13H13ClN4OS |
|---|---|
| Molecular Weight | 308.05 g/mol |
| LogP | 3.156 |
| Topological Polar Surface Area | 70.14 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 308.04987 |
| Heavy Atoms | 20 |
| Complexity | 671.47406 |
Chemical Identifiers
| CAS Number | 1285635-46-2 |
|---|---|
| SMILES | C/C(=N/NC(=O)C1=NNC(=C1)C2CC2)/C3=CC=C(S3)Cl |
Product Overview
(Z)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-3-cyclopropyl-1H-pyrazole-5-carbohydrazide (CAS 1285635-46-2), with molecular formula C13H13ClN4OS and molecular weight 308.05 g/mol. IUPAC: N-[(Z)-1-(5-chlorothiophen-2-yl)ethylideneamino]-5-cyclopropyl-1H-pyrazole-3-carboxamide.
Chemical Property Profile of (Z)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-3-cyclopropyl-1H-pyrazole-5-carbohydrazide
Property Insights of (Z)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-3-cyclopropyl-1H-pyrazole-5-carbohydrazide
The XLogP value of 3.156 indicates that (Z)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-3-cyclopropyl-1H-pyrazole-5-carbohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 70.14 Ų falls within the moderate polarity range, balancing permeability and solubility for (Z)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-3-cyclopropyl-1H-pyrazole-5-carbohydrazide. Following Lipinski's Rule of Five, (Z)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-3-cyclopropyl-1H-pyrazole-5-carbohydrazide has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (Z)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-3-cyclopropyl-1H-pyrazole-5-carbohydrazide?
The CAS number of (Z)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-3-cyclopropyl-1H-pyrazole-5-carbohydrazide is 1285635-46-2.
What is the molecular formula of (Z)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-3-cyclopropyl-1H-pyrazole-5-carbohydrazide?
The molecular formula of (Z)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-3-cyclopropyl-1H-pyrazole-5-carbohydrazide is C13H13ClN4OS.
What is the molecular weight of (Z)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-3-cyclopropyl-1H-pyrazole-5-carbohydrazide?
The molecular weight of (Z)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-3-cyclopropyl-1H-pyrazole-5-carbohydrazide is 308.05 g/mol.
Where can I buy (Z)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-3-cyclopropyl-1H-pyrazole-5-carbohydrazide?
You can request a quote for (Z)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-3-cyclopropyl-1H-pyrazole-5-carbohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (Z)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-3-cyclopropyl-1H-pyrazole-5-carbohydrazide?
Yes, KEHONG BIO provides custom synthesis services for (Z)-N'-(1-(5-chlorothiophen-2-yl)ethylidene)-3-cyclopropyl-1H-pyrazole-5-carbohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.