6-Methoxypodophyllotoxin
TL;DR: 6-Methoxypodophyllotoxin (CAS 128443-52-7) is a chemical compound with molecular formula C23H24O9 and molecular weight 444.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5R,5aR,8aR,9R)-5-hydroxy-4-methoxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one
Also Known As: 5-Methoxypodophyllotoxin, 6-methoxypodophyllotoxin, (5R,5aR,8aR,9R)-5-hydroxy-4-methoxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one, (5R-(5alpha,5abeta,8aalpha,9alpha))-5,8,8a,9-Tetrahydro-9-hydroxy-10-methoxy-5-(3,4,5-trimethoxyphenyl)furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-10-methoxy-5-(3,4,5-trimethoxyphenyl)-, (5R-(5alpha,5abeta,8aalpha,9alpha))-
| Molecular Formula | C23H24O9 |
|---|---|
| Molecular Weight | 444.14 g/mol |
| LogP | 2.4178 |
| Topological Polar Surface Area | 101.91 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 5 |
| Exact Mass | 444.14203 |
| Heavy Atoms | 32 |
| Complexity | 1054.6172 |
Chemical Identifiers
| CAS Number | 128443-52-7 |
|---|---|
| SMILES | COC1=CC(=CC(=C1OC)OC)[C@H]2[C@@H]3[C@H](COC3=O)[C@H](C4=C(C5=C(C=C24)OCO5)OC)O |
Product Overview
6-Methoxypodophyllotoxin (CAS 128443-52-7), with molecular formula C23H24O9 and molecular weight 444.14 g/mol. IUPAC: (5R,5aR,8aR,9R)-5-hydroxy-4-methoxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one.
Chemical Property Profile of 6-Methoxypodophyllotoxin
Property Insights of 6-Methoxypodophyllotoxin
The XLogP value of 2.4178 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 6-Methoxypodophyllotoxin. The TPSA of 101.91 Ų falls within the moderate polarity range, balancing permeability and solubility for 6-Methoxypodophyllotoxin. Following Lipinski's Rule of Five, 6-Methoxypodophyllotoxin has 1 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-Methoxypodophyllotoxin?
The CAS number of 6-Methoxypodophyllotoxin is 128443-52-7.
What is the molecular formula of 6-Methoxypodophyllotoxin?
The molecular formula of 6-Methoxypodophyllotoxin is C23H24O9.
What is the molecular weight of 6-Methoxypodophyllotoxin?
The molecular weight of 6-Methoxypodophyllotoxin is 444.14 g/mol.
Where can I buy 6-Methoxypodophyllotoxin?
You can request a quote for 6-Methoxypodophyllotoxin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-Methoxypodophyllotoxin?
Yes, KEHONG BIO provides custom synthesis services for 6-Methoxypodophyllotoxin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.