trans-1,4,4a,6,7,8,9,11a-Octahydropyrido(2,1-b)quinazolin-11-one structure

trans-1,4,4a,6,7,8,9,11a-Octahydropyrido(2,1-b)quinazolin-11-one

TL;DR: trans-1,4,4a,6,7,8,9,11a-Octahydropyrido(2,1-b)quinazolin-11-one (CAS 128349-77-9) is a chemical compound with molecular formula C12H16N2O and molecular weight 204.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(4aS,11aS)-1,4,4a,6,7,8,9,11a-octahydropyrido[2,1-b]quinazolin-11-one

Also Known As: trans-1,4,4a,6,7,8,9,11a-Octahydropyrido(2,1-b)quinazolin-11-one, 11H-Pyrido(2,1-b)quinazolin-11-one, 1,4,4a,6,7,8,9,11a-octahydro-, trans-, 1,4,4a,6,7,8,9,11a-Octahydro-11H-pyrido[2,1-b]quinazolin-11-one, (4aS,11aS)-1,4,4a,6,7,8,9,11a-octahydro-11H-pyrido[2,1-b]quinazolin-11-one, (4aS,11aS)-1,4,4a,6,7,8,9,11a-octahydropyrido[2,1-b]quinazolin-11-one

CAS: 128349-77-9
Molecular Formula C12H16N2O
Molecular Weight 204.13 g/mol
LogP 0.8
Topological Polar Surface Area 32.7 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 2
Rotatable Bonds 0
Exact Mass 204.12627
Heavy Atoms 15
Complexity 346.0

Chemical Identifiers

CAS Number 128349-77-9
SMILES C1CCN2C(=N[C@H]3CC=CC[C@@H]3C2=O)C1
InChIKey AKNLDGCUHGJHEW-UWVGGRQHSA-N

Product Overview

trans-1,4,4a,6,7,8,9,11a-Octahydropyrido(2,1-b)quinazolin-11-one (CAS 128349-77-9), with molecular formula C12H16N2O and molecular weight 204.13 g/mol. IUPAC: (4aS,11aS)-1,4,4a,6,7,8,9,11a-octahydropyrido[2,1-b]quinazolin-11-one.

🧪
Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of trans-1,4,4a,6,7,8,9,11a-Octahydropyrido(2,1-b)quinazolin-11-one

XLogP
0.8
TPSA (Topological Polar Surface Area)
32.7
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
2
Rotatable Bonds
0
Heavy Atoms
15
Complexity
346.0
Exact Mass
204.12627
Monoisotopic Mass
204.12627
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of trans-1,4,4a,6,7,8,9,11a-Octahydropyrido(2,1-b)quinazolin-11-one

The XLogP value of 0.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for trans-1,4,4a,6,7,8,9,11a-Octahydropyrido(2,1-b)quinazolin-11-one. With a topological polar surface area (TPSA) of 32.7 Ų, trans-1,4,4a,6,7,8,9,11a-Octahydropyrido(2,1-b)quinazolin-11-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, trans-1,4,4a,6,7,8,9,11a-Octahydropyrido(2,1-b)quinazolin-11-one has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of trans-1,4,4a,6,7,8,9,11a-Octahydropyrido(2,1-b)quinazolin-11-one?

The CAS number of trans-1,4,4a,6,7,8,9,11a-Octahydropyrido(2,1-b)quinazolin-11-one is 128349-77-9.

What is the molecular formula of trans-1,4,4a,6,7,8,9,11a-Octahydropyrido(2,1-b)quinazolin-11-one?

The molecular formula of trans-1,4,4a,6,7,8,9,11a-Octahydropyrido(2,1-b)quinazolin-11-one is C12H16N2O.

What is the molecular weight of trans-1,4,4a,6,7,8,9,11a-Octahydropyrido(2,1-b)quinazolin-11-one?

The molecular weight of trans-1,4,4a,6,7,8,9,11a-Octahydropyrido(2,1-b)quinazolin-11-one is 204.13 g/mol.

Where can I buy trans-1,4,4a,6,7,8,9,11a-Octahydropyrido(2,1-b)quinazolin-11-one?

You can request a quote for trans-1,4,4a,6,7,8,9,11a-Octahydropyrido(2,1-b)quinazolin-11-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for trans-1,4,4a,6,7,8,9,11a-Octahydropyrido(2,1-b)quinazolin-11-one?

Yes, KEHONG BIO provides custom synthesis services for trans-1,4,4a,6,7,8,9,11a-Octahydropyrido(2,1-b)quinazolin-11-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

🤖 科弘生物 AI 助手 ×
您好!我是 科弘生物 AI 助手。可以问我产品搜索、询价、样品或技术问题。如何帮助您?