2-Amino-4-chloro-5-fluoropyrimidine
TL;DR: 2-Amino-4-chloro-5-fluoropyrimidine (CAS 128071-75-0) is a chemical compound with molecular formula C4H3ClFN3 and molecular weight 147.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-chloro-5-fluoropyrimidin-2-amine
Also Known As: 2-Amino-4-chloro-5-fluoropyrimidine, 4-chloro-5-fluoropyrimidin-2-amine, Camobucol, 4-Chloro-5-fluoro-2-pyrimidinamine, 2-pyrimidinamine, 4-chloro-5-fluoro-
| Molecular Formula | C4H3ClFN3 |
|---|---|
| Molecular Weight | 147.00 g/mol |
| LogP | 0.9 |
| Topological Polar Surface Area | 51.8 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 0 |
| Exact Mass | 146.99995 |
| Heavy Atoms | 9 |
| Complexity | 102.0 |
Chemical Identifiers
| CAS Number | 128071-75-0 |
|---|---|
| SMILES | C1=C(C(=NC(=N1)N)Cl)F |
| InChIKey | JJSZXRDRSOBWAD-UHFFFAOYSA-N |
Product Overview
2-Amino-4-chloro-5-fluoropyrimidine (CAS 128071-75-0), with molecular formula C4H3ClFN3 and molecular weight 147.00 g/mol. IUPAC: 4-chloro-5-fluoropyrimidin-2-amine.
Chemical Property Profile of 2-Amino-4-chloro-5-fluoropyrimidine
Property Insights of 2-Amino-4-chloro-5-fluoropyrimidine
The XLogP value of 0.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-Amino-4-chloro-5-fluoropyrimidine. With a topological polar surface area (TPSA) of 51.8 Ų, 2-Amino-4-chloro-5-fluoropyrimidine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-Amino-4-chloro-5-fluoropyrimidine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-Amino-4-chloro-5-fluoropyrimidine?
The CAS number of 2-Amino-4-chloro-5-fluoropyrimidine is 128071-75-0.
What is the molecular formula of 2-Amino-4-chloro-5-fluoropyrimidine?
The molecular formula of 2-Amino-4-chloro-5-fluoropyrimidine is C4H3ClFN3.
What is the molecular weight of 2-Amino-4-chloro-5-fluoropyrimidine?
The molecular weight of 2-Amino-4-chloro-5-fluoropyrimidine is 147.00 g/mol.
Where can I buy 2-Amino-4-chloro-5-fluoropyrimidine?
You can request a quote for 2-Amino-4-chloro-5-fluoropyrimidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-Amino-4-chloro-5-fluoropyrimidine?
Yes, KEHONG BIO provides custom synthesis services for 2-Amino-4-chloro-5-fluoropyrimidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.