17,20,21-Trihydroxypregn-4-en-3-one, (20R)- structure

17,20,21-Trihydroxypregn-4-en-3-one, (20R)-

TL;DR: 17,20,21-Trihydroxypregn-4-en-3-one, (20R)- (CAS 128-19-8) is a chemical compound with molecular formula C21H32O4 and molecular weight 348.23 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(8R,9S,10R,13S,14S,17R)-17-[(1R)-1,2-dihydroxyethyl]-17-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one

Also Known As: 17alpha-Pregnenetriolone, 17,20,21-Trihydroxypregn-4-en-3-one, (20R)-, 4-Pregnene-17alpha,20beta,21-triol-3-one, 4-Pregnene-17alpha,20beta,21-triol-3-one [MI], Pregn-4-en-3-one, 17,20,21-trihydroxy-, (20R)-

CAS: 128-19-8
Molecular Formula C21H32O4
Molecular Weight 348.23 g/mol
LogP 2.6026
Topological Polar Surface Area 77.76 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 4
Rotatable Bonds 2
Exact Mass 348.23007
Heavy Atoms 25
Complexity 613.01733

Chemical Identifiers

CAS Number 128-19-8
SMILES C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@@]4([C@@H](CO)O)O)C

Product Overview

17,20,21-Trihydroxypregn-4-en-3-one, (20R)- (CAS 128-19-8), with molecular formula C21H32O4 and molecular weight 348.23 g/mol. IUPAC: (8R,9S,10R,13S,14S,17R)-17-[(1R)-1,2-dihydroxyethyl]-17-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one.

🧪
Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 17,20,21-Trihydroxypregn-4-en-3-one, (20R)-

XLogP
2.6026
TPSA (Topological Polar Surface Area)
77.76
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
4
Rotatable Bonds
2
Heavy Atoms
25
Complexity
613.01733
Exact Mass
348.23007
Monoisotopic Mass
348.23007
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 17,20,21-Trihydroxypregn-4-en-3-one, (20R)-

The XLogP value of 2.6026 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 17,20,21-Trihydroxypregn-4-en-3-one, (20R)-. The TPSA of 77.76 Ų falls within the moderate polarity range, balancing permeability and solubility for 17,20,21-Trihydroxypregn-4-en-3-one, (20R)-. Following Lipinski's Rule of Five, 17,20,21-Trihydroxypregn-4-en-3-one, (20R)- has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 17,20,21-Trihydroxypregn-4-en-3-one, (20R)-?

The CAS number of 17,20,21-Trihydroxypregn-4-en-3-one, (20R)- is 128-19-8.

What is the molecular formula of 17,20,21-Trihydroxypregn-4-en-3-one, (20R)-?

The molecular formula of 17,20,21-Trihydroxypregn-4-en-3-one, (20R)- is C21H32O4.

What is the molecular weight of 17,20,21-Trihydroxypregn-4-en-3-one, (20R)-?

The molecular weight of 17,20,21-Trihydroxypregn-4-en-3-one, (20R)- is 348.23 g/mol.

Where can I buy 17,20,21-Trihydroxypregn-4-en-3-one, (20R)-?

You can request a quote for 17,20,21-Trihydroxypregn-4-en-3-one, (20R)- directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 17,20,21-Trihydroxypregn-4-en-3-one, (20R)-?

Yes, KEHONG BIO provides custom synthesis services for 17,20,21-Trihydroxypregn-4-en-3-one, (20R)- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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