2'-deoxy-2'-amino-ara-toyocamycin
TL;DR: 2'-deoxy-2'-amino-ara-toyocamycin (CAS 127880-86-8) is a chemical compound with molecular formula C12H14N6O3 and molecular weight 290.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-amino-7-[(2R,3S,4S,5R)-3-amino-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carbonitrile
Also Known As: 2'-deoxy-2'-amino-ara-toyocamycin, 4-Amino-7-((2R,3S,4S,5R)-3-amino-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile, 4-Amino-7-(3-amino-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-7H-pyrrolo(2,3-d)pyrimidine-5-carbonitrile, 4-amino-5-cyano-7-(2-deoxy-2-amino-EC-D-arabinofuranosyl)pyrrolo<2,3-d>pyrimidine, 4-Amino-7-(2-amino-2-deoxypentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile
| Molecular Formula | C12H14N6O3 |
|---|---|
| Molecular Weight | 290.11 g/mol |
| LogP | -1.53692 |
| Topological Polar Surface Area | 156.23 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 2 |
| Exact Mass | 290.11273 |
| Heavy Atoms | 21 |
| Complexity | 723.5864 |
Chemical Identifiers
| CAS Number | 127880-86-8 |
|---|---|
| SMILES | C1=C(C2=C(N=CN=C2N1[C@H]3[C@H]([C@@H]([C@H](O3)CO)O)N)N)C#N |
Product Overview
2'-deoxy-2'-amino-ara-toyocamycin (CAS 127880-86-8), with molecular formula C12H14N6O3 and molecular weight 290.11 g/mol. IUPAC: 4-amino-7-[(2R,3S,4S,5R)-3-amino-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carbonitrile.
Chemical Property Profile of 2'-deoxy-2'-amino-ara-toyocamycin
Property Insights of 2'-deoxy-2'-amino-ara-toyocamycin
The XLogP value of -1.53692 indicates that 2'-deoxy-2'-amino-ara-toyocamycin is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 156.23 Ų indicates high polarity, suggesting 2'-deoxy-2'-amino-ara-toyocamycin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 2'-deoxy-2'-amino-ara-toyocamycin has 4 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2'-deoxy-2'-amino-ara-toyocamycin?
The CAS number of 2'-deoxy-2'-amino-ara-toyocamycin is 127880-86-8.
What is the molecular formula of 2'-deoxy-2'-amino-ara-toyocamycin?
The molecular formula of 2'-deoxy-2'-amino-ara-toyocamycin is C12H14N6O3.
What is the molecular weight of 2'-deoxy-2'-amino-ara-toyocamycin?
The molecular weight of 2'-deoxy-2'-amino-ara-toyocamycin is 290.11 g/mol.
Where can I buy 2'-deoxy-2'-amino-ara-toyocamycin?
You can request a quote for 2'-deoxy-2'-amino-ara-toyocamycin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2'-deoxy-2'-amino-ara-toyocamycin?
Yes, KEHONG BIO provides custom synthesis services for 2'-deoxy-2'-amino-ara-toyocamycin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.