(alphaR)-alpha-Methyl-3,5-bis(trifluoromethyl)benzenemethanol
TL;DR: (alphaR)-alpha-Methyl-3,5-bis(trifluoromethyl)benzenemethanol (CAS 127852-28-2) is a chemical compound with molecular formula C10H8F6O and molecular weight 258.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethanol
Also Known As: (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol, (r)-1-(3,5-bis(trifluoromethyl)phenyl)ethanol, Aprepitant Impurity 37, Aprepitant Impurity 38, zlchem 1281
| Molecular Formula | C10H8F6O |
|---|---|
| Molecular Weight | 258.05 g/mol |
| LogP | 3.7775 |
| Topological Polar Surface Area | 20.23 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 1 |
| Exact Mass | 258.04794 |
| Heavy Atoms | 17 |
| Complexity | 371.98764 |
Chemical Identifiers
| CAS Number | 127852-28-2 |
|---|---|
| SMILES | C[C@H](C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)O |
Product Overview
(alphaR)-alpha-Methyl-3,5-bis(trifluoromethyl)benzenemethanol (CAS 127852-28-2), with molecular formula C10H8F6O and molecular weight 258.05 g/mol. IUPAC: (1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethanol.
Chemical Property Profile of (alphaR)-alpha-Methyl-3,5-bis(trifluoromethyl)benzenemethanol
Property Insights of (alphaR)-alpha-Methyl-3,5-bis(trifluoromethyl)benzenemethanol
The XLogP value of 3.7775 indicates that (alphaR)-alpha-Methyl-3,5-bis(trifluoromethyl)benzenemethanol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 20.23 Ų, (alphaR)-alpha-Methyl-3,5-bis(trifluoromethyl)benzenemethanol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (alphaR)-alpha-Methyl-3,5-bis(trifluoromethyl)benzenemethanol has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (alphaR)-alpha-Methyl-3,5-bis(trifluoromethyl)benzenemethanol?
The CAS number of (alphaR)-alpha-Methyl-3,5-bis(trifluoromethyl)benzenemethanol is 127852-28-2.
What is the molecular formula of (alphaR)-alpha-Methyl-3,5-bis(trifluoromethyl)benzenemethanol?
The molecular formula of (alphaR)-alpha-Methyl-3,5-bis(trifluoromethyl)benzenemethanol is C10H8F6O.
What is the molecular weight of (alphaR)-alpha-Methyl-3,5-bis(trifluoromethyl)benzenemethanol?
The molecular weight of (alphaR)-alpha-Methyl-3,5-bis(trifluoromethyl)benzenemethanol is 258.05 g/mol.
Where can I buy (alphaR)-alpha-Methyl-3,5-bis(trifluoromethyl)benzenemethanol?
You can request a quote for (alphaR)-alpha-Methyl-3,5-bis(trifluoromethyl)benzenemethanol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (alphaR)-alpha-Methyl-3,5-bis(trifluoromethyl)benzenemethanol?
Yes, KEHONG BIO provides custom synthesis services for (alphaR)-alpha-Methyl-3,5-bis(trifluoromethyl)benzenemethanol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.