![1-[3,4-Difluoro-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione structure](/static/products/1278/127840-99-7.webp)
1-[3,4-Difluoro-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
TL;DR: 1-[3,4-Difluoro-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione (CAS 127840-99-7) is a chemical compound with molecular formula C9H10F2N2O4 and molecular weight 248.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[3,4-difluoro-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
Also Known As: Uridine,2',3'-dideoxy-2',3'-difluoro- (9CI), 1-[3,4-difluoro-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione, 1-(2,3-dideoxy-2,3-difluoropentofuranosyl)pyrimidine-2,4(1H,3H)-dione
| Molecular Formula | C9H10F2N2O4 |
|---|---|
| Molecular Weight | 248.06 g/mol |
| LogP | -0.5 |
| Topological Polar Surface Area | 78.9 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 248.06087 |
| Heavy Atoms | 17 |
| Complexity | 376.0 |
Chemical Identifiers
| CAS Number | 127840-99-7 |
|---|---|
| SMILES | C1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)F)F |
| InChIKey | ZACSMWVJEMXZMV-UHFFFAOYSA-N |
Product Overview
1-[3,4-Difluoro-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione (CAS 127840-99-7), with molecular formula C9H10F2N2O4 and molecular weight 248.06 g/mol. IUPAC: 1-[3,4-difluoro-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione.
Chemical Property Profile of 1-[3,4-Difluoro-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
Property Insights of 1-[3,4-Difluoro-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
The XLogP value of -0.5 indicates that 1-[3,4-Difluoro-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 78.9 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-[3,4-Difluoro-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione. Following Lipinski's Rule of Five, 1-[3,4-Difluoro-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-[3,4-Difluoro-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione?
The CAS number of 1-[3,4-Difluoro-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione is 127840-99-7.
What is the molecular formula of 1-[3,4-Difluoro-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione?
The molecular formula of 1-[3,4-Difluoro-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione is C9H10F2N2O4.
What is the molecular weight of 1-[3,4-Difluoro-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione?
The molecular weight of 1-[3,4-Difluoro-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione is 248.06 g/mol.
Where can I buy 1-[3,4-Difluoro-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione?
You can request a quote for 1-[3,4-Difluoro-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-[3,4-Difluoro-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione?
Yes, KEHONG BIO provides custom synthesis services for 1-[3,4-Difluoro-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.