3'-Azido-2',3'-dideoxy-2'-fluoro-5-methyluridine
TL;DR: 3'-Azido-2',3'-dideoxy-2'-fluoro-5-methyluridine (CAS 127840-94-2) is a chemical compound with molecular formula C10H12FN5O4 and molecular weight 285.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(2R,3R,4R,5S)-4-azido-3-fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
Also Known As: AZdd-2'-F-methyl-U, Fluorinated Sugar Analog, 3'-Azido-2',3'-dideoxy-2'-fluoro-5-methyluridine, 3'-Azido-3'-deoxy-2'-fluorothymidine, Uridine, 3'-azido-2',3'-dideoxy-2'-fluoro-5-methyl-
| Molecular Formula | C10H12FN5O4 |
|---|---|
| Molecular Weight | 285.09 g/mol |
| LogP | 0.1 |
| Topological Polar Surface Area | 93.2 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 3 |
| Exact Mass | 285.08734 |
| Heavy Atoms | 20 |
| Complexity | 518.0 |
Chemical Identifiers
| CAS Number | 127840-94-2 |
|---|---|
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)N=[N+]=[N-])F |
| InChIKey | AVYGFRQPURLSLQ-JXOAFFINSA-N |
Product Overview
3'-Azido-2',3'-dideoxy-2'-fluoro-5-methyluridine (CAS 127840-94-2), with molecular formula C10H12FN5O4 and molecular weight 285.09 g/mol. IUPAC: 1-[(2R,3R,4R,5S)-4-azido-3-fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione.
Chemical Property Profile of 3'-Azido-2',3'-dideoxy-2'-fluoro-5-methyluridine
Property Insights of 3'-Azido-2',3'-dideoxy-2'-fluoro-5-methyluridine
The XLogP value of 0.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 3'-Azido-2',3'-dideoxy-2'-fluoro-5-methyluridine. The TPSA of 93.2 Ų falls within the moderate polarity range, balancing permeability and solubility for 3'-Azido-2',3'-dideoxy-2'-fluoro-5-methyluridine. Following Lipinski's Rule of Five, 3'-Azido-2',3'-dideoxy-2'-fluoro-5-methyluridine has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3'-Azido-2',3'-dideoxy-2'-fluoro-5-methyluridine?
The CAS number of 3'-Azido-2',3'-dideoxy-2'-fluoro-5-methyluridine is 127840-94-2.
What is the molecular formula of 3'-Azido-2',3'-dideoxy-2'-fluoro-5-methyluridine?
The molecular formula of 3'-Azido-2',3'-dideoxy-2'-fluoro-5-methyluridine is C10H12FN5O4.
What is the molecular weight of 3'-Azido-2',3'-dideoxy-2'-fluoro-5-methyluridine?
The molecular weight of 3'-Azido-2',3'-dideoxy-2'-fluoro-5-methyluridine is 285.09 g/mol.
Where can I buy 3'-Azido-2',3'-dideoxy-2'-fluoro-5-methyluridine?
You can request a quote for 3'-Azido-2',3'-dideoxy-2'-fluoro-5-methyluridine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3'-Azido-2',3'-dideoxy-2'-fluoro-5-methyluridine?
Yes, KEHONG BIO provides custom synthesis services for 3'-Azido-2',3'-dideoxy-2'-fluoro-5-methyluridine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.