Cyclic HPMPC
TL;DR: Cyclic HPMPC (CAS 127757-45-3) is a chemical compound with molecular formula C8H12N3O5P and molecular weight 261.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-amino-1-[[(5S)-2-hydroxy-2-oxo-1,4,2λ5-dioxaphosphinan-5-yl]methyl]pyrimidin-2-one
Also Known As: Chpmpc, Cyclic-hpmpc, Cyclic HPMPC, cCDV, CYCLIC CIDOFOVIR
| Molecular Formula | C8H12N3O5P |
|---|---|
| Molecular Weight | 261.05 g/mol |
| LogP | -2.6 |
| Topological Polar Surface Area | 114.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 261.05145 |
| Heavy Atoms | 17 |
| Complexity | 435.0 |
Chemical Identifiers
| CAS Number | 127757-45-3 |
|---|---|
| SMILES | C1[C@@H](OCP(=O)(O1)O)CN2C=CC(=NC2=O)N |
| InChIKey | YXQUGSXUDFTPLL-LURJTMIESA-N |
Patent-Derived Application Labels
Derived from 4 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Cyclic HPMPC (CAS 127757-45-3), with molecular formula C8H12N3O5P and molecular weight 261.05 g/mol. IUPAC: 4-amino-1-[[(5S)-2-hydroxy-2-oxo-1,4,2λ5-dioxaphosphinan-5-yl]methyl]pyrimidin-2-one.
Chemical Property Profile of Cyclic HPMPC
Property Insights of Cyclic HPMPC
The XLogP value of -2.6 indicates that Cyclic HPMPC is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 114.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Cyclic HPMPC. Following Lipinski's Rule of Five, Cyclic HPMPC has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Cyclic HPMPC?
The CAS number of Cyclic HPMPC is 127757-45-3.
What is the molecular formula of Cyclic HPMPC?
The molecular formula of Cyclic HPMPC is C8H12N3O5P.
What is the molecular weight of Cyclic HPMPC?
The molecular weight of Cyclic HPMPC is 261.05 g/mol.
Where can I buy Cyclic HPMPC?
You can request a quote for Cyclic HPMPC directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Cyclic HPMPC?
Yes, KEHONG BIO provides custom synthesis services for Cyclic HPMPC and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.