1-(4-Azido-2-fluoro-3-methoxycyclopentyl)thymine-triphosphate structure

1-(4-Azido-2-fluoro-3-methoxycyclopentyl)thymine-triphosphate

TL;DR: 1-(4-Azido-2-fluoro-3-methoxycyclopentyl)thymine-triphosphate (CAS 127753-53-1) is a chemical compound with molecular formula C11H17FN5O12P3 and molecular weight 523.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[[(1S,2S,3S,5S)-5-azido-2-fluoro-3-(5-methyl-2,4-dioxopyrimidin-1-yl)cyclopentyl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

Also Known As: 4-Az-2-F-3-MeOCyclopentTTP, 1-(4-Azido-2-fluoro-3-methoxycyclopentyl)thymine-triphosphate, Triphosphoric acid, P-((5-azido-3-(3,4-dihydro-5-methyl-2,4-dioxo-1(2H)-pyrimidinyl)-2-fluorocyclopentyl)methyl) ester, (1alpha,2beta,3alpha,5beta)-, compd. with N,N-diethylethanamine, [[(1S,2S,3S,5S)-5-azido-2-fluoro-3-(5-methyl-2,4-dioxo-pyrimidin-1-yl)cyclopentyl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate, [[(1S,2S,3S,5S)-5-azido-2-fluoro-3-(5-methyl-2,4-dioxopyrimidin-1-yl)cyclopentyl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

CAS: 127753-53-1
Molecular Formula C11H17FN5O12P3
Molecular Weight 523.01 g/mol
LogP -2.6
Topological Polar Surface Area 224.0 Ų
Hydrogen Bond Donors 5
Hydrogen Bond Acceptors 15
Rotatable Bonds 9
Exact Mass 523.0071
Heavy Atoms 32
Complexity 1010.0

Chemical Identifiers

CAS Number 127753-53-1
SMILES CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H]([C@@H]2F)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)N=[N+]=[N-]
InChIKey CMHHWJSQNNZORY-XGEHTFHBSA-N

Product Overview

1-(4-Azido-2-fluoro-3-methoxycyclopentyl)thymine-triphosphate (CAS 127753-53-1), with molecular formula C11H17FN5O12P3 and molecular weight 523.01 g/mol. IUPAC: [[(1S,2S,3S,5S)-5-azido-2-fluoro-3-(5-methyl-2,4-dioxopyrimidin-1-yl)cyclopentyl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 1-(4-Azido-2-fluoro-3-methoxycyclopentyl)thymine-triphosphate

XLogP
-2.6
TPSA (Topological Polar Surface Area)
224.0
Hydrogen Bond Donors
5
Hydrogen Bond Acceptors
15
Rotatable Bonds
9
Heavy Atoms
32
Complexity
1010.0
Exact Mass
523.0071
Monoisotopic Mass
523.0071
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 1-(4-Azido-2-fluoro-3-methoxycyclopentyl)thymine-triphosphate

The XLogP value of -2.6 indicates that 1-(4-Azido-2-fluoro-3-methoxycyclopentyl)thymine-triphosphate is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 224.0 Ų indicates high polarity, suggesting 1-(4-Azido-2-fluoro-3-methoxycyclopentyl)thymine-triphosphate may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 1-(4-Azido-2-fluoro-3-methoxycyclopentyl)thymine-triphosphate has 5 hydrogen bond donor(s) and 15 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 1-(4-Azido-2-fluoro-3-methoxycyclopentyl)thymine-triphosphate?

The CAS number of 1-(4-Azido-2-fluoro-3-methoxycyclopentyl)thymine-triphosphate is 127753-53-1.

What is the molecular formula of 1-(4-Azido-2-fluoro-3-methoxycyclopentyl)thymine-triphosphate?

The molecular formula of 1-(4-Azido-2-fluoro-3-methoxycyclopentyl)thymine-triphosphate is C11H17FN5O12P3.

What is the molecular weight of 1-(4-Azido-2-fluoro-3-methoxycyclopentyl)thymine-triphosphate?

The molecular weight of 1-(4-Azido-2-fluoro-3-methoxycyclopentyl)thymine-triphosphate is 523.01 g/mol.

Where can I buy 1-(4-Azido-2-fluoro-3-methoxycyclopentyl)thymine-triphosphate?

You can request a quote for 1-(4-Azido-2-fluoro-3-methoxycyclopentyl)thymine-triphosphate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 1-(4-Azido-2-fluoro-3-methoxycyclopentyl)thymine-triphosphate?

Yes, KEHONG BIO provides custom synthesis services for 1-(4-Azido-2-fluoro-3-methoxycyclopentyl)thymine-triphosphate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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