GM2 (神经节苷脂) structure

GM2 (神经节苷脂)

TL;DR: GM2 (神经节苷脂) (CAS 127663-77-8) is a chemical compound with molecular formula C67H121N3O26 and molecular weight 1383.82 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

GM2 (神经节苷脂)

(2S,4S,5R,6R)-5-acetamido-2-[(2S,3R,4R,5S,6R)-5-[(2S,3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-[(2R,3S,4R,5R,6R)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(E,2S,3R)-3-hydroxy-2-(octadecanoylamino)octadec-4-enoxy]oxan-3-yl]oxy-3-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid

Also Known As: Ganglioside GM2, GM2 lipid, GM2 ganglioside, Tay-Sachs ganglioside, G(M2) GANGLIOSIDE

CAS: 127663-77-8
Molecular Formula C67H121N3O26
Molecular Weight 1383.82 g/mol
LogP 1.1334
Topological Polar Surface Area 461.43 Ų
Hydrogen Bond Donors 17
Hydrogen Bond Acceptors 25
Rotatable Bonds 49
Exact Mass 1383.8239
Heavy Atoms 96
Complexity 2176.191

Chemical Identifiers

CAS Number 127663-77-8
SMILES CCCCCCCCCCCCCCCCCC(=O)N[C@@H](CO[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)CO)O[C@H]3[C@@H]([C@H]([C@H]([C@H](O3)CO)O)O)NC(=O)C)O[C@@]4(C[C@@H]([C@H]([C@@H](O4)[C@@H]([C@@H](CO)O)O)NC(=O)C)O)C(=O)O)O)O)O)[C@@H](/C=C/CCCCCCCCCCCCC)O

Product Overview

GM2 (神经节苷脂) (CAS 127663-77-8), with molecular formula C67H121N3O26 and molecular weight 1383.82 g/mol. IUPAC: (2S,4S,5R,6R)-5-acetamido-2-[(2S,3R,4R,5S,6R)-5-[(2S,3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-[(2R,3S,4R,5R,6R)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(E,2S,3R)-3-hydroxy-2-(octadecanoylamino)octadec-4-enoxy]oxan-3-yl]oxy-3-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of GM2 (神经节苷脂)

XLogP
1.1334
TPSA (Topological Polar Surface Area)
461.43
Hydrogen Bond Donors
17
Hydrogen Bond Acceptors
25
Rotatable Bonds
49
Heavy Atoms
96
Complexity
2176.191
Exact Mass
1383.8239
Monoisotopic Mass
1383.8239
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of GM2 (神经节苷脂)

The XLogP value of 1.1334 suggests moderate lipophilicity, balancing water solubility and membrane permeability for GM2 (神经节苷脂). The TPSA of 461.43 Ų indicates high polarity, suggesting GM2 (神经节苷脂) may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, GM2 (神经节苷脂) has 17 hydrogen bond donor(s) and 25 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of GM2 (神经节苷脂)?

The CAS number of GM2 (神经节苷脂) is 127663-77-8.

What is the molecular formula of GM2 (神经节苷脂)?

The molecular formula of GM2 (神经节苷脂) is C67H121N3O26.

What is the molecular weight of GM2 (神经节苷脂)?

The molecular weight of GM2 (神经节苷脂) is 1383.82 g/mol.

Where can I buy GM2 (神经节苷脂)?

You can request a quote for GM2 (神经节苷脂) directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for GM2 (神经节苷脂)?

Yes, KEHONG BIO provides custom synthesis services for GM2 (神经节苷脂) and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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