N(5)-piperazine-amiloride
TL;DR: N(5)-piperazine-amiloride (CAS 127628-91-5) is a chemical compound with molecular formula C10H15ClN8O and molecular weight 298.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-amino-6-chloro-N-(diaminomethylidene)-5-piperazin-1-ylpyrazine-2-carboxamide
Also Known As: N(5)-Piperazine-amiloride, N(5)-Piperazinylamiloride, N(5)-Pyrazinylamiloride, 3-amino-6-chloro-N-(diaminomethylidene)-5-piperazin-1-ylpyrazine-2-carboxamide, 2-Pyrazinecarboxamide, 3-amino-N-(aminoiminomethyl)-6-chloro-5-(1-piperazinyl)-
| Molecular Formula | C10H15ClN8O |
|---|---|
| Molecular Weight | 298.11 g/mol |
| LogP | -0.6 |
| Topological Polar Surface Area | 149.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 298.10574 |
| Heavy Atoms | 20 |
| Complexity | 381.0 |
Chemical Identifiers
| CAS Number | 127628-91-5 |
|---|---|
| SMILES | C1CN(CCN1)C2=NC(=C(N=C2Cl)C(=O)N=C(N)N)N |
| InChIKey | OJANHPFPUXFRED-UHFFFAOYSA-N |
Product Overview
N(5)-piperazine-amiloride (CAS 127628-91-5), with molecular formula C10H15ClN8O and molecular weight 298.11 g/mol. IUPAC: 3-amino-6-chloro-N-(diaminomethylidene)-5-piperazin-1-ylpyrazine-2-carboxamide.
Chemical Property Profile of N(5)-piperazine-amiloride
Property Insights of N(5)-piperazine-amiloride
The XLogP value of -0.6 indicates that N(5)-piperazine-amiloride is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 149.0 Ų indicates high polarity, suggesting N(5)-piperazine-amiloride may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, N(5)-piperazine-amiloride has 4 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N(5)-piperazine-amiloride?
The CAS number of N(5)-piperazine-amiloride is 127628-91-5.
What is the molecular formula of N(5)-piperazine-amiloride?
The molecular formula of N(5)-piperazine-amiloride is C10H15ClN8O.
What is the molecular weight of N(5)-piperazine-amiloride?
The molecular weight of N(5)-piperazine-amiloride is 298.11 g/mol.
Where can I buy N(5)-piperazine-amiloride?
You can request a quote for N(5)-piperazine-amiloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N(5)-piperazine-amiloride?
Yes, KEHONG BIO provides custom synthesis services for N(5)-piperazine-amiloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.