Clarithromycin 9-Oxime
TL;DR: Clarithromycin 9-Oxime (CAS 127253-05-8) is a chemical compound with molecular formula C38H70N2O13 and molecular weight 762.49 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-12,13-dihydroxy-10-hydroxyimino-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-7-methoxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecan-2-one
Also Known As: Clarithromycin 9-Oxime, Clarithromycin E-9-Oxime, Clarithromycin (9Z)-Oxime, Clarithromycin oxime, Clarithromycin Impurity L
| Molecular Formula | C38H70N2O13 |
|---|---|
| Molecular Weight | 762.49 g/mol |
| LogP | 2.7008 |
| Topological Polar Surface Area | 198.43 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 15 |
| Rotatable Bonds | 8 |
| Exact Mass | 762.4878 |
| Heavy Atoms | 53 |
| Complexity | 1222.4714 |
Chemical Identifiers
| CAS Number | 127253-05-8 |
|---|---|
| SMILES | CC[C@@H]1[C@@]([C@@H]([C@H](/C(=N/O)/[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)OC)C)C)O)(C)O |
Product Overview
Clarithromycin 9-Oxime (CAS 127253-05-8), with molecular formula C38H70N2O13 and molecular weight 762.49 g/mol. IUPAC: (3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-12,13-dihydroxy-10-hydroxyimino-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-7-methoxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecan-2-one.
Chemical Property Profile of Clarithromycin 9-Oxime
Property Insights of Clarithromycin 9-Oxime
The XLogP value of 2.7008 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Clarithromycin 9-Oxime. The TPSA of 198.43 Ų indicates high polarity, suggesting Clarithromycin 9-Oxime may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Clarithromycin 9-Oxime has 5 hydrogen bond donor(s) and 15 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Clarithromycin 9-Oxime?
The CAS number of Clarithromycin 9-Oxime is 127253-05-8.
What is the molecular formula of Clarithromycin 9-Oxime?
The molecular formula of Clarithromycin 9-Oxime is C38H70N2O13.
What is the molecular weight of Clarithromycin 9-Oxime?
The molecular weight of Clarithromycin 9-Oxime is 762.49 g/mol.
Where can I buy Clarithromycin 9-Oxime?
You can request a quote for Clarithromycin 9-Oxime directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Clarithromycin 9-Oxime?
Yes, KEHONG BIO provides custom synthesis services for Clarithromycin 9-Oxime and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.