2'-Tbdms-dmfg
TL;DR: 2'-Tbdms-dmfg (CAS 126922-67-6) is a chemical compound with molecular formula C23H39N6O7PSi and molecular weight 570.24 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[(E)-but-2-enyl] [(2R,3R,4R,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-[2-[(E)-dimethylaminomethylideneamino]purin-9-yl]-3-hydroxyoxolan-2-yl]methyl hydrogen phosphate
Also Known As: 2'-Tbdms-dmfg, n-Butyl 2'-dimethyl-tert-butylsilyl-N(2)-(N,N-dimethylamino)methylene-guanosine 3,',5'-cyclic phosphate, [(E)-but-2-enyl] [(2R,3R,4R,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-[2-[(E)-dimethylaminomethylideneamino]purin-9-yl]-3-hydroxyoxolan-2-yl]methyl hydrogen phosphate, Guanosine, N-((dimethylamino)methylene)-2'-O-((1,1-dimethylethyl)dimethylsilyl)-, cyclic 3',5'-(butylphosphate), (S)-, n-butyl 2/'-dimethyl-tert-butylsilyl-N(2)-(N,N-dimethylamino)methylene-guanosine 3,/',5/'-cyclic pho
| Molecular Formula | C23H39N6O7PSi |
|---|---|
| Molecular Weight | 570.24 g/mol |
| LogP | 3.4061 |
| Topological Polar Surface Area | 153.65 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 11 |
| Exact Mass | 570.2387 |
| Heavy Atoms | 38 |
| Complexity | 1198.62 |
Chemical Identifiers
| CAS Number | 126922-67-6 |
|---|---|
| SMILES | C/C=C/COP(=O)(O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=CN=C(N=C32)/N=C/N(C)C)O[Si](C)(C)C(C)(C)C)O |
Product Overview
2'-Tbdms-dmfg (CAS 126922-67-6), with molecular formula C23H39N6O7PSi and molecular weight 570.24 g/mol. IUPAC: [(E)-but-2-enyl] [(2R,3R,4R,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-[2-[(E)-dimethylaminomethylideneamino]purin-9-yl]-3-hydroxyoxolan-2-yl]methyl hydrogen phosphate.
Chemical Property Profile of 2'-Tbdms-dmfg
Property Insights of 2'-Tbdms-dmfg
The XLogP value of 3.4061 indicates that 2'-Tbdms-dmfg is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 153.65 Ų indicates high polarity, suggesting 2'-Tbdms-dmfg may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 2'-Tbdms-dmfg has 2 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2'-Tbdms-dmfg?
The CAS number of 2'-Tbdms-dmfg is 126922-67-6.
What is the molecular formula of 2'-Tbdms-dmfg?
The molecular formula of 2'-Tbdms-dmfg is C23H39N6O7PSi.
What is the molecular weight of 2'-Tbdms-dmfg?
The molecular weight of 2'-Tbdms-dmfg is 570.24 g/mol.
Where can I buy 2'-Tbdms-dmfg?
You can request a quote for 2'-Tbdms-dmfg directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2'-Tbdms-dmfg?
Yes, KEHONG BIO provides custom synthesis services for 2'-Tbdms-dmfg and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.