2-Tbdms-phosphoramidate
TL;DR: 2-Tbdms-phosphoramidate (CAS 126922-65-4) is a chemical compound with molecular formula C23H40N7O6PSi and molecular weight 569.25 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[(2R,3R,4R,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-[2-(dimethylaminomethylideneamino)purin-9-yl]-3-hydroxyoxolan-2-yl]methoxy-N-ethenyl-N-ethylphosphonamidic acid
Also Known As: 2-Tbdms-phosphoramidate, 2'-Dimethyl-tert-butylsilyl-N(2)-(N,N-dimethylamino)methylene-guanosine 3',5'-cyclic diethylphosphoramidate
| Molecular Formula | C23H40N7O6PSi |
|---|---|
| Molecular Weight | 569.25 g/mol |
| LogP | 3.2788 |
| Topological Polar Surface Area | 147.66 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 11 |
| Exact Mass | 569.2547 |
| Heavy Atoms | 38 |
| Complexity | 1200.62 |
Chemical Identifiers
| CAS Number | 126922-65-4 |
|---|---|
| SMILES | CCN(C=C)P(=O)(O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=CN=C(N=C32)N=CN(C)C)O[Si](C)(C)C(C)(C)C)O |
Product Overview
2-Tbdms-phosphoramidate (CAS 126922-65-4), with molecular formula C23H40N7O6PSi and molecular weight 569.25 g/mol. IUPAC: [(2R,3R,4R,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-[2-(dimethylaminomethylideneamino)purin-9-yl]-3-hydroxyoxolan-2-yl]methoxy-N-ethenyl-N-ethylphosphonamidic acid.
Chemical Property Profile of 2-Tbdms-phosphoramidate
Property Insights of 2-Tbdms-phosphoramidate
The XLogP value of 3.2788 indicates that 2-Tbdms-phosphoramidate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 147.66 Ų indicates high polarity, suggesting 2-Tbdms-phosphoramidate may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 2-Tbdms-phosphoramidate has 2 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-Tbdms-phosphoramidate?
The CAS number of 2-Tbdms-phosphoramidate is 126922-65-4.
What is the molecular formula of 2-Tbdms-phosphoramidate?
The molecular formula of 2-Tbdms-phosphoramidate is C23H40N7O6PSi.
What is the molecular weight of 2-Tbdms-phosphoramidate?
The molecular weight of 2-Tbdms-phosphoramidate is 569.25 g/mol.
Where can I buy 2-Tbdms-phosphoramidate?
You can request a quote for 2-Tbdms-phosphoramidate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-Tbdms-phosphoramidate?
Yes, KEHONG BIO provides custom synthesis services for 2-Tbdms-phosphoramidate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.