(R)-(+)-Terfenadine
TL;DR: (R)-(+)-Terfenadine (CAS 126830-75-9) is a chemical compound with molecular formula C32H41NO2 and molecular weight 471.31 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(1R)-1-(4-tert-butylphenyl)-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butan-1-ol
Also Known As: terfenadine, (R)-(+)-Terfenadine, Terfenadine, (R)-, Terfenadine, (+)-, (+)-Terfenadine
| Molecular Formula | C32H41NO2 |
|---|---|
| Molecular Weight | 471.31 g/mol |
| LogP | 6.4458 |
| Topological Polar Surface Area | 43.7 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 8 |
| Exact Mass | 471.31372 |
| Heavy Atoms | 35 |
| Complexity | 992.93115 |
Chemical Identifiers
| CAS Number | 126830-75-9 |
|---|---|
| SMILES | CC(C)(C)C1=CC=C(C=C1)[C@@H](CCCN2CCC(CC2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O)O |
Product Overview
(R)-(+)-Terfenadine (CAS 126830-75-9), with molecular formula C32H41NO2 and molecular weight 471.31 g/mol. IUPAC: (1R)-1-(4-tert-butylphenyl)-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butan-1-ol.
Chemical Property Profile of (R)-(+)-Terfenadine
Property Insights of (R)-(+)-Terfenadine
The XLogP value of 6.4458 indicates that (R)-(+)-Terfenadine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 43.7 Ų, (R)-(+)-Terfenadine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (R)-(+)-Terfenadine has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (R)-(+)-Terfenadine?
The CAS number of (R)-(+)-Terfenadine is 126830-75-9.
What is the molecular formula of (R)-(+)-Terfenadine?
The molecular formula of (R)-(+)-Terfenadine is C32H41NO2.
What is the molecular weight of (R)-(+)-Terfenadine?
The molecular weight of (R)-(+)-Terfenadine is 471.31 g/mol.
Where can I buy (R)-(+)-Terfenadine?
You can request a quote for (R)-(+)-Terfenadine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (R)-(+)-Terfenadine?
Yes, KEHONG BIO provides custom synthesis services for (R)-(+)-Terfenadine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.