Calicheamicinone structure

Calicheamicinone

TL;DR: Calicheamicinone (CAS 126629-10-5) is a chemical compound with molecular formula C18H17NO5S3 and molecular weight 423.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

methyl N-[(1R,4Z,8S,13Z)-1,8-dihydroxy-13-[2-(methyltrisulfanyl)ethylidene]-11-oxo-10-bicyclo[7.3.1]trideca-4,9-dien-2,6-diynyl]carbamate

Also Known As: Calicheamicinone, methyl N-[(1R,4Z,8S,13Z)-1,8-dihydroxy-13-[2-(methyltrisulfanyl)ethylidene]-11-oxo-10-bicyclo[7.3.1]trideca-4,9-dien-2,6-diynyl]carbamate

CAS: 126629-10-5
Molecular Formula C18H17NO5S3
Molecular Weight 423.03 g/mol
LogP 1.8237
Topological Polar Surface Area 95.86 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 8
Rotatable Bonds 5
Exact Mass 423.0269
Heavy Atoms 27
Complexity 840.52905

Chemical Identifiers

CAS Number 126629-10-5
SMILES COC(=O)NC1=C\2[C@H](C#C/C=C\C#C[C@@](/C2=C\CSSSC)(CC1=O)O)O

Product Overview

Calicheamicinone (CAS 126629-10-5), with molecular formula C18H17NO5S3 and molecular weight 423.03 g/mol. IUPAC: methyl N-[(1R,4Z,8S,13Z)-1,8-dihydroxy-13-[2-(methyltrisulfanyl)ethylidene]-11-oxo-10-bicyclo[7.3.1]trideca-4,9-dien-2,6-diynyl]carbamate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Calicheamicinone

XLogP
1.8237
TPSA (Topological Polar Surface Area)
95.86
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
8
Rotatable Bonds
5
Heavy Atoms
27
Complexity
840.52905
Exact Mass
423.0269
Monoisotopic Mass
423.0269
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Calicheamicinone

The XLogP value of 1.8237 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Calicheamicinone. The TPSA of 95.86 Ų falls within the moderate polarity range, balancing permeability and solubility for Calicheamicinone. Following Lipinski's Rule of Five, Calicheamicinone has 3 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Calicheamicinone?

The CAS number of Calicheamicinone is 126629-10-5.

What is the molecular formula of Calicheamicinone?

The molecular formula of Calicheamicinone is C18H17NO5S3.

What is the molecular weight of Calicheamicinone?

The molecular weight of Calicheamicinone is 423.03 g/mol.

Where can I buy Calicheamicinone?

You can request a quote for Calicheamicinone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Calicheamicinone?

Yes, KEHONG BIO provides custom synthesis services for Calicheamicinone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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