Validamycin E structure

Validamycin E

TL;DR: Validamycin E (CAS 12650-71-4) is a chemical compound with molecular formula C26H45NO18 and molecular weight 659.26 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-[6-[2,3-dihydroxy-6-(hydroxymethyl)-4-[[4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino]cyclohexyl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol

Also Known As: Validamycin E, Validamycin C, 2-[6-[2,3-dihydroxy-6-(hydroxymethyl)-4-[[4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino]cyclohexyl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol, D-chiro-Inositol, O-alpha-D-glucopyranosyl-(1-4)-O-beta-D-glucopyranosyl-(1-3)-1,5,6-trideoxy-5-(hydroxymethyl)-1-((4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl)amino)-, (1S-(1-alpha,4-alpha,5-beta,6-alpha))-, 4-O-[4-O-(alpha-D-Glucopyranosyl)-beta-D-glucopyranosyl]-5-(hydroxymethyl)-1-[[(1S,4R,5S,6S)-4,5,6-trihydro

CAS: 12650-71-4
Molecular Formula C26H45NO18
Molecular Weight 659.26 g/mol
LogP -8.4
Topological Polar Surface Area 332.0 Ų
Hydrogen Bond Donors 15
Hydrogen Bond Acceptors 19
Rotatable Bonds 10
Exact Mass 659.2637
Heavy Atoms 45
Complexity 978.0

Chemical Identifiers

CAS Number 12650-71-4
SMILES C1C(C(C(C(C1NC2C=C(C(C(C2O)O)O)CO)O)O)OC3C(C(C(C(O3)CO)OC4C(C(C(C(O4)CO)O)O)O)O)O)CO
InChIKey MSZAIRLAOKNKFW-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.

Pharmaceutical Intermediates (2 patents)

Product Overview

Validamycin E (CAS 12650-71-4), with molecular formula C26H45NO18 and molecular weight 659.26 g/mol. IUPAC: 2-[6-[2,3-dihydroxy-6-(hydroxymethyl)-4-[[4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino]cyclohexyl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Validamycin E

XLogP
-8.4
TPSA (Topological Polar Surface Area)
332.0
Hydrogen Bond Donors
15
Hydrogen Bond Acceptors
19
Rotatable Bonds
10
Heavy Atoms
45
Complexity
978.0
Exact Mass
659.2637
Monoisotopic Mass
659.2637
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Validamycin E

The XLogP value of -8.4 indicates that Validamycin E is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 332.0 Ų indicates high polarity, suggesting Validamycin E may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Validamycin E has 15 hydrogen bond donor(s) and 19 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Validamycin E?

The CAS number of Validamycin E is 12650-71-4.

What is the molecular formula of Validamycin E?

The molecular formula of Validamycin E is C26H45NO18.

What is the molecular weight of Validamycin E?

The molecular weight of Validamycin E is 659.26 g/mol.

Where can I buy Validamycin E?

You can request a quote for Validamycin E directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Validamycin E?

Yes, KEHONG BIO provides custom synthesis services for Validamycin E and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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