Colistin sulfate (USP:JAN)
TL;DR: Colistin sulfate (USP:JAN) (CAS 1264-72-8) is a chemical compound with molecular formula C53H102N16O17S and molecular weight 1266.73 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(2S)-4-amino-1-[[(2S,3R)-1-[[(2S)-4-amino-1-oxo-1-[[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-3-[(1R)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]-6-methyloctanamide;sulfuric acid
Also Known As: Colistin sulfate, Belcomycin, Colomycin syrup, Coly-Mycin S, Colimycin sulfate
| Molecular Formula | C53H102N16O17S |
|---|---|
| Molecular Weight | 1266.73 g/mol |
| LogP | -6.09 |
| Topological Polar Surface Area | 574.0 Ų |
| Hydrogen Bond Donors | 20 |
| Hydrogen Bond Acceptors | 22 |
| Rotatable Bonds | 29 |
| Exact Mass | 1266.7329 |
| Heavy Atoms | 87 |
| Complexity | 2150.0 |
Chemical Identifiers
| CAS Number | 1264-72-8 |
|---|---|
| SMILES | CCC(C)CCCCC(=O)N[C@@H](CCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCN)C(=O)N[C@H]1CCNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@@H](NC1=O)CCN)CC(C)C)CC(C)C)CCN)CCN)[C@@H](C)O.OS(=O)(=O)O |
| InChIKey | ZJIWRHLZXQPFAD-LRYSGCCDSA-N |
Product Overview
Colistin sulfate (USP:JAN) (CAS 1264-72-8), with molecular formula C53H102N16O17S and molecular weight 1266.73 g/mol. IUPAC: N-[(2S)-4-amino-1-[[(2S,3R)-1-[[(2S)-4-amino-1-oxo-1-[[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-3-[(1R)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]-6-methyloctanamide;sulfuric acid.
Chemical Property Profile of Colistin sulfate (USP:JAN)
Property Insights of Colistin sulfate (USP:JAN)
The XLogP value of -6.09 indicates that Colistin sulfate (USP:JAN) is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 574.0 Ų indicates high polarity, suggesting Colistin sulfate (USP:JAN) may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Colistin sulfate (USP:JAN) has 20 hydrogen bond donor(s) and 22 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Colistin sulfate (USP:JAN)?
The CAS number of Colistin sulfate (USP:JAN) is 1264-72-8.
What is the molecular formula of Colistin sulfate (USP:JAN)?
The molecular formula of Colistin sulfate (USP:JAN) is C53H102N16O17S.
What is the molecular weight of Colistin sulfate (USP:JAN)?
The molecular weight of Colistin sulfate (USP:JAN) is 1266.73 g/mol.
Where can I buy Colistin sulfate (USP:JAN)?
You can request a quote for Colistin sulfate (USP:JAN) directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Colistin sulfate (USP:JAN)?
Yes, KEHONG BIO provides custom synthesis services for Colistin sulfate (USP:JAN) and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.