Simarolide structure

Simarolide

TL;DR: Simarolide (CAS 1260-58-8) is a chemical compound with molecular formula C27H36O9 and molecular weight 504.24 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[(1S,2S,4S,6R,7S,9R,13R,14R,16R,17S)-4-hydroxy-2,6,14,17-tetramethyl-3,11-dioxo-14-[(3R)-5-oxooxolane-3-carbonyl]-10-oxatetracyclo[7.7.1.02,7.013,17]heptadecan-16-yl] acetate

Also Known As: (2beta,3beta,4alpha)-2,3-Dihydroxy-27-norolean-13-ene-23,28-dioic acid, [(1S,2S,4S,6R,7S,9R,13R,14R,16R,17S)-4-hydroxy-2,6,14,17-tetramethyl-3,11-dioxo-14-[(3R)-5-oxooxolane-3-carbonyl]-10-oxatetracyclo[7.7.1.02,7.013,17]heptadecan-16-yl] acetate, 2-Hydroxy-1,16-dioxo-13-(5-oxooxolane-3-carbonyl)picrasan-11-yl acetate, 24-Nor-16,17-secocholane-16,23-dioic acid, 11-(acetyloxy)-2,7,21-trihydroxy-4,8-dimethyl-1,17-dioxo-, gamma-lactone delta-lactone, (2alpha,4alpha,5alpha,7alpha,11alpha,13alpha,14beta,20R)-, 2alpha-Hydroxy-1,16-dioxo-13-[(3R)-5-oxooxolane-3-carbonyl]picrasan-11alpha-yl acetate

CAS: 1260-58-8
Molecular Formula C27H36O9
Molecular Weight 504.24 g/mol
LogP 2.0105
Topological Polar Surface Area 133.27 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 9
Rotatable Bonds 3
Exact Mass 504.23593
Heavy Atoms 36
Complexity 1036.2617

Chemical Identifiers

CAS Number 1260-58-8
SMILES C[C@@H]1C[C@@H](C(=O)[C@]2([C@H]1C[C@@H]3[C@@]4([C@@H]2[C@@H](C[C@@]([C@@H]4CC(=O)O3)(C)C(=O)[C@@H]5CC(=O)OC5)OC(=O)C)C)C)O

Product Overview

Simarolide (CAS 1260-58-8), with molecular formula C27H36O9 and molecular weight 504.24 g/mol. IUPAC: [(1S,2S,4S,6R,7S,9R,13R,14R,16R,17S)-4-hydroxy-2,6,14,17-tetramethyl-3,11-dioxo-14-[(3R)-5-oxooxolane-3-carbonyl]-10-oxatetracyclo[7.7.1.02,7.013,17]heptadecan-16-yl] acetate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Simarolide

XLogP
2.0105
TPSA (Topological Polar Surface Area)
133.27
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
9
Rotatable Bonds
3
Heavy Atoms
36
Complexity
1036.2617
Exact Mass
504.23593
Monoisotopic Mass
504.23593
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Simarolide

The XLogP value of 2.0105 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Simarolide. The TPSA of 133.27 Ų falls within the moderate polarity range, balancing permeability and solubility for Simarolide. Following Lipinski's Rule of Five, Simarolide has 1 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Simarolide?

The CAS number of Simarolide is 1260-58-8.

What is the molecular formula of Simarolide?

The molecular formula of Simarolide is C27H36O9.

What is the molecular weight of Simarolide?

The molecular weight of Simarolide is 504.24 g/mol.

Where can I buy Simarolide?

You can request a quote for Simarolide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Simarolide?

Yes, KEHONG BIO provides custom synthesis services for Simarolide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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