SK&F R-106114 structure

SK&F R-106114

TL;DR: SK&F R-106114 (CAS 125375-99-7) is a chemical compound with molecular formula C21H25ClN2O2 and molecular weight 372.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

9-chloro-7,8-diethyl-5-(4-hydroxyphenyl)-1,2,4,5-tetrahydro-3-benzazepine-3-carboxamide

Also Known As: Skf-R-106114, SK&F R-106114, 6-Chloro-7,8-diethylcarbamoyl-1-(4'-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine, 9-chloro-7,8-diethyl-5-(4-hydroxyphenyl)-1,2,4,5-tetrahydro-3-benzazepine-3-carboxamide, 6-Chloro-7,8-diethyl-1-(4-hydroxyphenyl)-1,2,4,5-tetrahydro-3H-3-benzazepine-3-carboximidic acid

CAS: 125375-99-7
Molecular Formula C21H25ClN2O2
Molecular Weight 372.16 g/mol
LogP 4.5
Topological Polar Surface Area 66.6 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 2
Rotatable Bonds 3
Exact Mass 372.16046
Heavy Atoms 26
Complexity 481.0

Chemical Identifiers

CAS Number 125375-99-7
SMILES CCC1=CC2=C(CCN(CC2C3=CC=C(C=C3)O)C(=O)N)C(=C1CC)Cl
InChIKey RWUJULIRPAQPNY-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (1 patents) Pharmaceutical Intermediates (1 patents)

Product Overview

SK&F R-106114 (CAS 125375-99-7), with molecular formula C21H25ClN2O2 and molecular weight 372.16 g/mol. IUPAC: 9-chloro-7,8-diethyl-5-(4-hydroxyphenyl)-1,2,4,5-tetrahydro-3-benzazepine-3-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of SK&F R-106114

XLogP
4.5
TPSA (Topological Polar Surface Area)
66.6
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
2
Rotatable Bonds
3
Heavy Atoms
26
Complexity
481.0
Exact Mass
372.16046
Monoisotopic Mass
372.16046
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of SK&F R-106114

The XLogP value of 4.5 indicates that SK&F R-106114 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 66.6 Ų falls within the moderate polarity range, balancing permeability and solubility for SK&F R-106114. Following Lipinski's Rule of Five, SK&F R-106114 has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of SK&F R-106114?

The CAS number of SK&F R-106114 is 125375-99-7.

What is the molecular formula of SK&F R-106114?

The molecular formula of SK&F R-106114 is C21H25ClN2O2.

What is the molecular weight of SK&F R-106114?

The molecular weight of SK&F R-106114 is 372.16 g/mol.

Where can I buy SK&F R-106114?

You can request a quote for SK&F R-106114 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for SK&F R-106114?

Yes, KEHONG BIO provides custom synthesis services for SK&F R-106114 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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