LY-195448 (hydrochloride)
TL;DR: LY-195448 (hydrochloride) (CAS 125310-51-2) is a chemical compound with molecular formula C20H27ClN2O2 and molecular weight 362.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-[3-[[(2R)-2-hydroxy-2-phenylethyl]amino]-3-methylbutyl]benzamide;hydrochloride
Also Known As: LY-195448 (hydrochloride), LY195448 HCl, (R)-4-(3-((2-Hydroxy-2-phenethyl)amino)-3-methylbutyl)benzamide monohydrochloride, 4-[3-[[(2R)-2-hydroxy-2-phenylethyl]amino]-3-methylbutyl]benzamide;hydrochloride, 4-(3-(2-Hydroxy-2-phenyl)ethylamino-3-methylbutyl)benzamide
| Molecular Formula | C20H27ClN2O2 |
|---|---|
| Molecular Weight | 362.18 g/mol |
| LogP | 3.2417 |
| Topological Polar Surface Area | 75.4 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 8 |
| Exact Mass | 362.17612 |
| Heavy Atoms | 25 |
| Complexity | 383.0 |
Chemical Identifiers
| CAS Number | 125310-51-2 |
|---|---|
| SMILES | CC(C)(CCC1=CC=C(C=C1)C(=O)N)NC[C@@H](C2=CC=CC=C2)O.Cl |
| InChIKey | PFTVHDSGCARRKR-FERBBOLQSA-N |
Patent-Derived Application Labels
Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
LY-195448 (hydrochloride) (CAS 125310-51-2), with molecular formula C20H27ClN2O2 and molecular weight 362.18 g/mol. IUPAC: 4-[3-[[(2R)-2-hydroxy-2-phenylethyl]amino]-3-methylbutyl]benzamide;hydrochloride.
Chemical Property Profile of LY-195448 (hydrochloride)
Property Insights of LY-195448 (hydrochloride)
The XLogP value of 3.2417 indicates that LY-195448 (hydrochloride) is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 75.4 Ų falls within the moderate polarity range, balancing permeability and solubility for LY-195448 (hydrochloride). Following Lipinski's Rule of Five, LY-195448 (hydrochloride) has 4 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of LY-195448 (hydrochloride)?
The CAS number of LY-195448 (hydrochloride) is 125310-51-2.
What is the molecular formula of LY-195448 (hydrochloride)?
The molecular formula of LY-195448 (hydrochloride) is C20H27ClN2O2.
What is the molecular weight of LY-195448 (hydrochloride)?
The molecular weight of LY-195448 (hydrochloride) is 362.18 g/mol.
Where can I buy LY-195448 (hydrochloride)?
You can request a quote for LY-195448 (hydrochloride) directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for LY-195448 (hydrochloride)?
Yes, KEHONG BIO provides custom synthesis services for LY-195448 (hydrochloride) and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.