Isocolchicine structure

Isocolchicine

TL;DR: Isocolchicine (CAS 1246818-69-8) is a chemical compound with molecular formula C22H25NO6 and molecular weight 399.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

N-(1,2,3,9-tetramethoxy-10-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl)acetamide

Also Known As: Isocolchicine, iso-Colchicine-d3, Tetra-O-methylisocolchicinic acid, J3.071.030D, N-(1,2,3,9-tetramethoxy-10-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl)acetamide

CAS: 1246818-69-8
Molecular Formula C22H25NO6
Molecular Weight 399.17 g/mol
LogP 1.0
Topological Polar Surface Area 83.1 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 6
Rotatable Bonds 5
Exact Mass 399.16818
Heavy Atoms 29
Complexity 740.0

Chemical Identifiers

CAS Number 1246818-69-8
SMILES CC(=O)NC1CCC2=CC(=C(C(=C2C3=C1C=C(C(=O)C=C3)OC)OC)OC)OC
InChIKey MDYALASTPGGXQH-UHFFFAOYSA-N

Product Overview

Isocolchicine (CAS 1246818-69-8), with molecular formula C22H25NO6 and molecular weight 399.17 g/mol. IUPAC: N-(1,2,3,9-tetramethoxy-10-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl)acetamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Isocolchicine

XLogP
1.0
TPSA (Topological Polar Surface Area)
83.1
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
6
Rotatable Bonds
5
Heavy Atoms
29
Complexity
740.0
Exact Mass
399.16818
Monoisotopic Mass
399.16818
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Isocolchicine

The XLogP value of 1.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Isocolchicine. The TPSA of 83.1 Ų falls within the moderate polarity range, balancing permeability and solubility for Isocolchicine. Following Lipinski's Rule of Five, Isocolchicine has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Isocolchicine?

The CAS number of Isocolchicine is 1246818-69-8.

What is the molecular formula of Isocolchicine?

The molecular formula of Isocolchicine is C22H25NO6.

What is the molecular weight of Isocolchicine?

The molecular weight of Isocolchicine is 399.17 g/mol.

Where can I buy Isocolchicine?

You can request a quote for Isocolchicine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Isocolchicine?

Yes, KEHONG BIO provides custom synthesis services for Isocolchicine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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