Hydroxyzine monohydrochloride
TL;DR: Hydroxyzine monohydrochloride (CAS 1244-76-4) is a chemical compound with molecular formula C21H28Cl2N2O2 and molecular weight 410.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]ethanol;hydrochloride
Also Known As: Hydroxyzine hydrochloride, Hydroxyzine Hcl, Vistaril, hydroxyzine, Atarax
| Molecular Formula | C21H28Cl2N2O2 |
|---|---|
| Molecular Weight | 410.15 g/mol |
| LogP | 3.48 |
| Topological Polar Surface Area | 35.9 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 8 |
| Exact Mass | 410.15277 |
| Heavy Atoms | 27 |
| Complexity | 376.0 |
Chemical Identifiers
| CAS Number | 1244-76-4 |
|---|---|
| SMILES | C1CN(CCN1CCOCCO)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl |
| InChIKey | IPSVAUIEEPSJRZ-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 12 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Hydroxyzine monohydrochloride (CAS 1244-76-4), with molecular formula C21H28Cl2N2O2 and molecular weight 410.15 g/mol. IUPAC: 2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]ethanol;hydrochloride.
Chemical Property Profile of Hydroxyzine monohydrochloride
Property Insights of Hydroxyzine monohydrochloride
The XLogP value of 3.48 indicates that Hydroxyzine monohydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 35.9 Ų, Hydroxyzine monohydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Hydroxyzine monohydrochloride has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Hydroxyzine monohydrochloride?
The CAS number of Hydroxyzine monohydrochloride is 1244-76-4.
What is the molecular formula of Hydroxyzine monohydrochloride?
The molecular formula of Hydroxyzine monohydrochloride is C21H28Cl2N2O2.
What is the molecular weight of Hydroxyzine monohydrochloride?
The molecular weight of Hydroxyzine monohydrochloride is 410.15 g/mol.
Where can I buy Hydroxyzine monohydrochloride?
You can request a quote for Hydroxyzine monohydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Hydroxyzine monohydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Hydroxyzine monohydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.