Sertraline ketone, (R)-
TL;DR: Sertraline ketone, (R)- (CAS 124379-29-9) is a chemical compound with molecular formula C16H12Cl2O and molecular weight 290.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4R)-4-(3,4-dichlorophenyl)-3,4-dihydro-2H-naphthalen-1-one
Also Known As: Sertraline EP Impurity F, Sertraline ketone, (R)-, (R)-sertraline ketone, (R)-4-(3,4-Dichlorophenyl)-1-tetralone, (r)-4-(3,4-dichlorophenyl)-3,4-dihydronaphthalen-1(2h)-one
| Molecular Formula | C16H12Cl2O |
|---|---|
| Molecular Weight | 290.03 g/mol |
| LogP | 5.1018 |
| Topological Polar Surface Area | 17.07 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 1 |
| Exact Mass | 290.02652 |
| Heavy Atoms | 19 |
| Complexity | 648.9472 |
Chemical Identifiers
| CAS Number | 124379-29-9 |
|---|---|
| SMILES | C1CC(=O)C2=CC=CC=C2[C@H]1C3=CC(=C(C=C3)Cl)Cl |
Product Overview
Sertraline ketone, (R)- (CAS 124379-29-9), with molecular formula C16H12Cl2O and molecular weight 290.03 g/mol. IUPAC: (4R)-4-(3,4-dichlorophenyl)-3,4-dihydro-2H-naphthalen-1-one.
Chemical Property Profile of Sertraline ketone, (R)-
Property Insights of Sertraline ketone, (R)-
The XLogP value of 5.1018 indicates that Sertraline ketone, (R)- is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 17.07 Ų, Sertraline ketone, (R)- exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Sertraline ketone, (R)- has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Sertraline ketone, (R)-?
The CAS number of Sertraline ketone, (R)- is 124379-29-9.
What is the molecular formula of Sertraline ketone, (R)-?
The molecular formula of Sertraline ketone, (R)- is C16H12Cl2O.
What is the molecular weight of Sertraline ketone, (R)-?
The molecular weight of Sertraline ketone, (R)- is 290.03 g/mol.
Where can I buy Sertraline ketone, (R)-?
You can request a quote for Sertraline ketone, (R)- directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Sertraline ketone, (R)-?
Yes, KEHONG BIO provides custom synthesis services for Sertraline ketone, (R)- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.