11,18-Epoxy-6-hydroxy-3-oxoandrost-4-ene-17,18-carbolactone
TL;DR: 11,18-Epoxy-6-hydroxy-3-oxoandrost-4-ene-17,18-carbolactone (CAS 124251-90-7) is a chemical compound with molecular formula C20H24O5 and molecular weight 344.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S,5S,6S,8R,14R,15S,16S)-8-hydroxy-14-methyl-11-oxo-17-oxapentacyclo[14.2.1.01,5.06,15.09,14]nonadeca-9,12-diene-2-carboxylic acid
Also Known As: 6-OH-Aldosterone-lactone, 6-Hydroxyaldosterone-gamma-lactone, 11,18-Epoxy-6-hydroxy-3-oxoandrost-4-ene-17,18-carbolactone, 6-Hydroxy-3-oxo-11,18-epoxyandrosta-1,4-diene-17-carboxylic acid, Androst-4-ene-17-carboxylic acid, 11,18-epoxy-6,18-dihydroxy-3-oxo-, gamma-lactone, (6beta,11beta,17beta)-
| Molecular Formula | C20H24O5 |
|---|---|
| Molecular Weight | 344.16 g/mol |
| LogP | 1.9547 |
| Topological Polar Surface Area | 83.83 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 344.16238 |
| Heavy Atoms | 25 |
| Complexity | 723.59814 |
Chemical Identifiers
| CAS Number | 124251-90-7 |
|---|---|
| SMILES | C[C@]12C=CC(=O)C=C1[C@@H](C[C@@H]3[C@@H]2[C@@H]4CC5([C@H]3CC[C@@H]5C(=O)O)CO4)O |
Product Overview
11,18-Epoxy-6-hydroxy-3-oxoandrost-4-ene-17,18-carbolactone (CAS 124251-90-7), with molecular formula C20H24O5 and molecular weight 344.16 g/mol. IUPAC: (2S,5S,6S,8R,14R,15S,16S)-8-hydroxy-14-methyl-11-oxo-17-oxapentacyclo[14.2.1.01,5.06,15.09,14]nonadeca-9,12-diene-2-carboxylic acid.
Chemical Property Profile of 11,18-Epoxy-6-hydroxy-3-oxoandrost-4-ene-17,18-carbolactone
Property Insights of 11,18-Epoxy-6-hydroxy-3-oxoandrost-4-ene-17,18-carbolactone
The XLogP value of 1.9547 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 11,18-Epoxy-6-hydroxy-3-oxoandrost-4-ene-17,18-carbolactone. The TPSA of 83.83 Ų falls within the moderate polarity range, balancing permeability and solubility for 11,18-Epoxy-6-hydroxy-3-oxoandrost-4-ene-17,18-carbolactone. Following Lipinski's Rule of Five, 11,18-Epoxy-6-hydroxy-3-oxoandrost-4-ene-17,18-carbolactone has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 11,18-Epoxy-6-hydroxy-3-oxoandrost-4-ene-17,18-carbolactone?
The CAS number of 11,18-Epoxy-6-hydroxy-3-oxoandrost-4-ene-17,18-carbolactone is 124251-90-7.
What is the molecular formula of 11,18-Epoxy-6-hydroxy-3-oxoandrost-4-ene-17,18-carbolactone?
The molecular formula of 11,18-Epoxy-6-hydroxy-3-oxoandrost-4-ene-17,18-carbolactone is C20H24O5.
What is the molecular weight of 11,18-Epoxy-6-hydroxy-3-oxoandrost-4-ene-17,18-carbolactone?
The molecular weight of 11,18-Epoxy-6-hydroxy-3-oxoandrost-4-ene-17,18-carbolactone is 344.16 g/mol.
Where can I buy 11,18-Epoxy-6-hydroxy-3-oxoandrost-4-ene-17,18-carbolactone?
You can request a quote for 11,18-Epoxy-6-hydroxy-3-oxoandrost-4-ene-17,18-carbolactone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 11,18-Epoxy-6-hydroxy-3-oxoandrost-4-ene-17,18-carbolactone?
Yes, KEHONG BIO provides custom synthesis services for 11,18-Epoxy-6-hydroxy-3-oxoandrost-4-ene-17,18-carbolactone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.