4-(5-Chlorothiophen-2-yl)-1,3-thiazol-2-amine
TL;DR: 4-(5-Chlorothiophen-2-yl)-1,3-thiazol-2-amine (CAS 123971-45-9) is a chemical compound with molecular formula C7H5ClN2S2 and molecular weight 215.96 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(5-chlorothiophen-2-yl)-1,3-thiazol-2-amine
Also Known As: 2-Amino-4-(5-chlorothien-2-yl)thiazole, 4-(5-chlorothiophen-2-yl)-1,3-thiazol-2-amine, 4-(5-Chloro-2-thienyl)-1,3-thiazol-2-amine, 4-(5-Chlorothiophen-2-yl)thiazol-2-amine, Avatrombopag Impurity 4
| Molecular Formula | C7H5ClN2S2 |
|---|---|
| Molecular Weight | 215.96 g/mol |
| LogP | 2.9 |
| Topological Polar Surface Area | 95.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 215.95827 |
| Heavy Atoms | 12 |
| Complexity | 169.0 |
Chemical Identifiers
| CAS Number | 123971-45-9 |
|---|---|
| SMILES | C1=C(SC(=C1)Cl)C2=CSC(=N2)N |
| InChIKey | KZOUOGWZDXYEDI-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
4-(5-Chlorothiophen-2-yl)-1,3-thiazol-2-amine (CAS 123971-45-9), with molecular formula C7H5ClN2S2 and molecular weight 215.96 g/mol. IUPAC: 4-(5-chlorothiophen-2-yl)-1,3-thiazol-2-amine.
Chemical Property Profile of 4-(5-Chlorothiophen-2-yl)-1,3-thiazol-2-amine
Property Insights of 4-(5-Chlorothiophen-2-yl)-1,3-thiazol-2-amine
The XLogP value of 2.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-(5-Chlorothiophen-2-yl)-1,3-thiazol-2-amine. The TPSA of 95.4 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-(5-Chlorothiophen-2-yl)-1,3-thiazol-2-amine. Following Lipinski's Rule of Five, 4-(5-Chlorothiophen-2-yl)-1,3-thiazol-2-amine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(5-Chlorothiophen-2-yl)-1,3-thiazol-2-amine?
The CAS number of 4-(5-Chlorothiophen-2-yl)-1,3-thiazol-2-amine is 123971-45-9.
What is the molecular formula of 4-(5-Chlorothiophen-2-yl)-1,3-thiazol-2-amine?
The molecular formula of 4-(5-Chlorothiophen-2-yl)-1,3-thiazol-2-amine is C7H5ClN2S2.
What is the molecular weight of 4-(5-Chlorothiophen-2-yl)-1,3-thiazol-2-amine?
The molecular weight of 4-(5-Chlorothiophen-2-yl)-1,3-thiazol-2-amine is 215.96 g/mol.
Where can I buy 4-(5-Chlorothiophen-2-yl)-1,3-thiazol-2-amine?
You can request a quote for 4-(5-Chlorothiophen-2-yl)-1,3-thiazol-2-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(5-Chlorothiophen-2-yl)-1,3-thiazol-2-amine?
Yes, KEHONG BIO provides custom synthesis services for 4-(5-Chlorothiophen-2-yl)-1,3-thiazol-2-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.