Tyrosyl-alanyl-lysyl-arginine chloromethyl ketone structure

Tyrosyl-alanyl-lysyl-arginine chloromethyl ketone

TL;DR: Tyrosyl-alanyl-lysyl-arginine chloromethyl ketone (CAS 123496-54-8) is a chemical compound with molecular formula C25H41ClN8O5 and molecular weight 568.29 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2S)-6-amino-N-[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]-2-[[1-chloro-6-(diaminomethylideneamino)-2-oxohexan-3-yl]amino]hexanamide

Also Known As: Yakr-CK, Tyr-ala-lys-arg chloromethyl ketone, Tyrosyl-alanyl-lysyl-arginine chloromethyl ketone, (2S)-6-amino-N-[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]-2-[[1-chloro-6-(diaminomethylideneamino)-2-oxohexan-3-yl]amino]hexanamide, L-Lysinamide, L-tyrosyl-L-alanyl-N-(4-((aminoiminomethyl)amino)-1-(chloroacetyl)butyl)-

CAS: 123496-54-8
Molecular Formula C25H41ClN8O5
Molecular Weight 568.29 g/mol
LogP -1.2732
Topological Polar Surface Area 241.04 Ų
Hydrogen Bond Donors 8
Hydrogen Bond Acceptors 9
Rotatable Bonds 18
Exact Mass 568.2888
Heavy Atoms 39
Complexity 971.71454

Chemical Identifiers

CAS Number 123496-54-8
SMILES C[C@@H](C(=O)NC(=O)[C@H](CCCCN)NC(CCCN=C(N)N)C(=O)CCl)NC(=O)[C@H](CC1=CC=C(C=C1)O)N

Product Overview

Tyrosyl-alanyl-lysyl-arginine chloromethyl ketone (CAS 123496-54-8), with molecular formula C25H41ClN8O5 and molecular weight 568.29 g/mol. IUPAC: (2S)-6-amino-N-[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]-2-[[1-chloro-6-(diaminomethylideneamino)-2-oxohexan-3-yl]amino]hexanamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Tyrosyl-alanyl-lysyl-arginine chloromethyl ketone

XLogP
-1.2732
TPSA (Topological Polar Surface Area)
241.04
Hydrogen Bond Donors
8
Hydrogen Bond Acceptors
9
Rotatable Bonds
18
Heavy Atoms
39
Complexity
971.71454
Exact Mass
568.2888
Monoisotopic Mass
568.2888
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Tyrosyl-alanyl-lysyl-arginine chloromethyl ketone

The XLogP value of -1.2732 indicates that Tyrosyl-alanyl-lysyl-arginine chloromethyl ketone is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 241.04 Ų indicates high polarity, suggesting Tyrosyl-alanyl-lysyl-arginine chloromethyl ketone may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Tyrosyl-alanyl-lysyl-arginine chloromethyl ketone has 8 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Tyrosyl-alanyl-lysyl-arginine chloromethyl ketone?

The CAS number of Tyrosyl-alanyl-lysyl-arginine chloromethyl ketone is 123496-54-8.

What is the molecular formula of Tyrosyl-alanyl-lysyl-arginine chloromethyl ketone?

The molecular formula of Tyrosyl-alanyl-lysyl-arginine chloromethyl ketone is C25H41ClN8O5.

What is the molecular weight of Tyrosyl-alanyl-lysyl-arginine chloromethyl ketone?

The molecular weight of Tyrosyl-alanyl-lysyl-arginine chloromethyl ketone is 568.29 g/mol.

Where can I buy Tyrosyl-alanyl-lysyl-arginine chloromethyl ketone?

You can request a quote for Tyrosyl-alanyl-lysyl-arginine chloromethyl ketone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Tyrosyl-alanyl-lysyl-arginine chloromethyl ketone?

Yes, KEHONG BIO provides custom synthesis services for Tyrosyl-alanyl-lysyl-arginine chloromethyl ketone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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