4-Hydroxytriamterene
TL;DR: 4-Hydroxytriamterene (CAS 1226-52-4) is a chemical compound with molecular formula C12H11N7O and molecular weight 269.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(2,4,7-triaminopteridin-6-yl)phenol
Also Known As: 4-Hydroxy Triamterene, p-Hydroxytriamterene, 4-Hydroxytriamterene, para-Hydroxytriamterene, Hydroxy Triamterene
| Molecular Formula | C12H11N7O |
|---|---|
| Molecular Weight | 269.10 g/mol |
| LogP | 0.6 |
| Topological Polar Surface Area | 150.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 1 |
| Exact Mass | 269.1025 |
| Heavy Atoms | 20 |
| Complexity | 336.0 |
Chemical Identifiers
| CAS Number | 1226-52-4 |
|---|---|
| SMILES | C1=CC(=CC=C1C2=NC3=C(N=C(N=C3N=C2N)N)N)O |
| InChIKey | QNJVMSASTUDLGC-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
4-Hydroxytriamterene (CAS 1226-52-4), with molecular formula C12H11N7O and molecular weight 269.10 g/mol. IUPAC: 4-(2,4,7-triaminopteridin-6-yl)phenol.
Chemical Property Profile of 4-Hydroxytriamterene
Property Insights of 4-Hydroxytriamterene
The XLogP value of 0.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-Hydroxytriamterene. The TPSA of 150.0 Ų indicates high polarity, suggesting 4-Hydroxytriamterene may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 4-Hydroxytriamterene has 4 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-Hydroxytriamterene?
The CAS number of 4-Hydroxytriamterene is 1226-52-4.
What is the molecular formula of 4-Hydroxytriamterene?
The molecular formula of 4-Hydroxytriamterene is C12H11N7O.
What is the molecular weight of 4-Hydroxytriamterene?
The molecular weight of 4-Hydroxytriamterene is 269.10 g/mol.
Where can I buy 4-Hydroxytriamterene?
You can request a quote for 4-Hydroxytriamterene directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-Hydroxytriamterene?
Yes, KEHONG BIO provides custom synthesis services for 4-Hydroxytriamterene and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.