PD 122860 structure

PD 122860

TL;DR: PD 122860 (CAS 122576-86-7) is a chemical compound with molecular formula C23H20F3N3O4S and molecular weight 491.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

ethyl 5-cyano-6-methyl-2-(pyridin-4-ylsulfonylmethyl)-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate

Also Known As: Ethyl 5-cyano-1,4-dihydro-6-methyl-2-((4-pyridinylsulfonyl)methyl)-4-(2-(trifluoromethyl)phenyl)-3-pyridinecarboxylate, 3-Pyridinecarboxylicacid,5-cyano-1,4-dihydro-6-methyl-2-[(4-pyridinylsulfonyl)methyl]-4-[2-(trifluoromethyl)phenyl]-,ethyl ester, ethyl 5-cyano-6-methyl-2-(pyridin-4-ylsulfonylmethyl)-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate, 3-Pyridinecarboxylic acid, 5-cyano-1,4-dihydro-6-methyl-2-((4-pyridinylsulfonyl)methyl)-4-(2-(trifluoromethyl)phenyl)-, ethyl ester, (+-)-, Ethyl 5-cyano-6-methyl-2-((pyridin-4-ylsulfonyl)methyl)-4-(2-(trifluoromethyl)phenyl)-1,4-dihydropyridine-3-carboxylate

CAS: 122576-86-7
Molecular Formula C23H20F3N3O4S
Molecular Weight 491.11 g/mol
LogP 3.0
Topological Polar Surface Area 118.0 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 10
Rotatable Bonds 7
Exact Mass 491.11267
Heavy Atoms 34
Complexity 999.0

Chemical Identifiers

CAS Number 122576-86-7
SMILES CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2C(F)(F)F)C#N)C)CS(=O)(=O)C3=CC=NC=C3
InChIKey ZUAWKQNJMCYABQ-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (10 patents) Pharmaceutical Intermediates (4 patents)

Product Overview

PD 122860 (CAS 122576-86-7), with molecular formula C23H20F3N3O4S and molecular weight 491.11 g/mol. IUPAC: ethyl 5-cyano-6-methyl-2-(pyridin-4-ylsulfonylmethyl)-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of PD 122860

XLogP
3.0
TPSA (Topological Polar Surface Area)
118.0
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
10
Rotatable Bonds
7
Heavy Atoms
34
Complexity
999.0
Exact Mass
491.11267
Monoisotopic Mass
491.11267
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of PD 122860

The XLogP value of 3.0 indicates that PD 122860 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 118.0 Ų falls within the moderate polarity range, balancing permeability and solubility for PD 122860. Following Lipinski's Rule of Five, PD 122860 has 1 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of PD 122860?

The CAS number of PD 122860 is 122576-86-7.

What is the molecular formula of PD 122860?

The molecular formula of PD 122860 is C23H20F3N3O4S.

What is the molecular weight of PD 122860?

The molecular weight of PD 122860 is 491.11 g/mol.

Where can I buy PD 122860?

You can request a quote for PD 122860 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for PD 122860?

Yes, KEHONG BIO provides custom synthesis services for PD 122860 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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