Prepro-thyrotropin releasing hormone (160-169)
TL;DR: Prepro-thyrotropin releasing hormone (160-169) (CAS 122018-91-1) is a chemical compound with molecular formula C54H75N11O18S and molecular weight 1197.50 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-3-phenylpropanoyl]pyrrolidine-2-carbonyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-methylsulfanylbutanoyl]amino]-5-[[(2S)-1-[[(2S)-3-carboxy-1-[[(2S)-1-[[(1S,2R)-1-carboxy-2-hydroxypropyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
Also Known As: Trh-potentiating peptide, Prepro-thyrotropin releasing hormone (160-169), Prepro-trh (160-169), Prepro-TRH-(160-169), Ser-phe-pro-trp-met-glu-ser-asp-val-thr
| Molecular Formula | C54H75N11O18S |
|---|---|
| Molecular Weight | 1197.50 g/mol |
| LogP | -4.2 |
| Topological Polar Surface Area | 493.0 Ų |
| Hydrogen Bond Donors | 16 |
| Hydrogen Bond Acceptors | 20 |
| Rotatable Bonds | 34 |
| Exact Mass | 1197.5012 |
| Heavy Atoms | 84 |
| Complexity | 2310.0 |
Chemical Identifiers
| CAS Number | 122018-91-1 |
|---|---|
| SMILES | C[C@H]([C@@H](C(=O)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CC1=CNC2=CC=CC=C21)NC(=O)[C@@H]3CCCN3C(=O)[C@H](CC4=CC=CC=C4)NC(=O)[C@H](CO)N)O |
| InChIKey | MKFZPNIYKHRJLV-UKESGPLISA-N |
Product Overview
Prepro-thyrotropin releasing hormone (160-169) (CAS 122018-91-1), with molecular formula C54H75N11O18S and molecular weight 1197.50 g/mol. IUPAC: (4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-3-phenylpropanoyl]pyrrolidine-2-carbonyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-methylsulfanylbutanoyl]amino]-5-[[(2S)-1-[[(2S)-3-carboxy-1-[[(2S)-1-[[(1S,2R)-1-carboxy-2-hydroxypropyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-5-oxopentanoic acid.
Chemical Property Profile of Prepro-thyrotropin releasing hormone (160-169)
Property Insights of Prepro-thyrotropin releasing hormone (160-169)
The XLogP value of -4.2 indicates that Prepro-thyrotropin releasing hormone (160-169) is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 493.0 Ų indicates high polarity, suggesting Prepro-thyrotropin releasing hormone (160-169) may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Prepro-thyrotropin releasing hormone (160-169) has 16 hydrogen bond donor(s) and 20 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Prepro-thyrotropin releasing hormone (160-169)?
The CAS number of Prepro-thyrotropin releasing hormone (160-169) is 122018-91-1.
What is the molecular formula of Prepro-thyrotropin releasing hormone (160-169)?
The molecular formula of Prepro-thyrotropin releasing hormone (160-169) is C54H75N11O18S.
What is the molecular weight of Prepro-thyrotropin releasing hormone (160-169)?
The molecular weight of Prepro-thyrotropin releasing hormone (160-169) is 1197.50 g/mol.
Where can I buy Prepro-thyrotropin releasing hormone (160-169)?
You can request a quote for Prepro-thyrotropin releasing hormone (160-169) directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Prepro-thyrotropin releasing hormone (160-169)?
Yes, KEHONG BIO provides custom synthesis services for Prepro-thyrotropin releasing hormone (160-169) and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.