geldanamycin
TL;DR: geldanamycin (CAS 1217871-08-3) is a chemical compound with molecular formula C29H40N2O9 and molecular weight 560.27 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[(4Z,6Z,10Z)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl] carbamate
Also Known As: geldanamycin, [(4Z,6Z,10Z)-13-Hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl] carbamate, 13-Hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate, [(8Z,12Z,14Z)-6-hydroxy-5,11,21-trimethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl] carbamate, 13-Hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-ylcarbamate
| Molecular Formula | C29H40N2O9 |
|---|---|
| Molecular Weight | 560.27 g/mol |
| LogP | 2.4084 |
| Topological Polar Surface Area | 163.48 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 4 |
| Exact Mass | 560.2734 |
| Heavy Atoms | 40 |
| Complexity | 1148.1469 |
Chemical Identifiers
| CAS Number | 1217871-08-3 |
|---|---|
| SMILES | CC1CC(C(C(/C=C(\C(C(/C=C\C=C(/C(=O)NC2=CC(=O)C(=C(C1)C2=O)OC)\C)OC)OC(=O)N)/C)C)O)OC |
Product Overview
geldanamycin (CAS 1217871-08-3), with molecular formula C29H40N2O9 and molecular weight 560.27 g/mol. IUPAC: [(4Z,6Z,10Z)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl] carbamate.
Chemical Property Profile of geldanamycin
Property Insights of geldanamycin
The XLogP value of 2.4084 suggests moderate lipophilicity, balancing water solubility and membrane permeability for geldanamycin. The TPSA of 163.48 Ų indicates high polarity, suggesting geldanamycin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, geldanamycin has 3 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of geldanamycin?
The CAS number of geldanamycin is 1217871-08-3.
What is the molecular formula of geldanamycin?
The molecular formula of geldanamycin is C29H40N2O9.
What is the molecular weight of geldanamycin?
The molecular weight of geldanamycin is 560.27 g/mol.
Where can I buy geldanamycin?
You can request a quote for geldanamycin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for geldanamycin?
Yes, KEHONG BIO provides custom synthesis services for geldanamycin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.